Chronic exposure to volcanic environments and cancer incidence in the Azores, Portugal
Chronic exposure to volcanic environments and cancer incidence in the Azores, Portugal
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DOI：
10.1016/j.scitotenv.2006.01.024
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发表时间：
2006-08-15
影响因子：
9.8
通讯作者：
Rodrigues, Armindo
中科院分区：
文献类型：
--
作者：
Amaral, Andre;Rodrigues, Victor;Rodrigues, Armindo
火山环境是否对癌症发病率构成风险尚不清楚。我们在两个种群中调查了这个问题，一个来自火山活动活跃的地区(弗纳斯)，另一个来自300万年前以来没有火山活动的地区(圣玛丽亚)，两者都在亚速尔群岛。1991-2001年期间弗纳斯和圣玛丽亚人口的癌症发病率数据来自当地保健中心的医疗记录。估计了年龄标化率和相对风险。当观察所有癌症和两性合并时，火山活跃区的总体发病率更高。然而，非火山活动区的消化、呼吸和胸腔内器官癌症的发病率较高，主要发生在男性，而火山活动区的唇癌、口腔癌和咽癌的发病率较高，无论男女，还是女性乳腺癌。两个人群之间的相对风险估计表明，Furns某些器官组的癌症风险较高，特别是唇癌、口腔癌和咽癌以及乳腺癌，这可能部分是由于长期暴露于火山活动造成的环境因素，如有害气体和气溶胶，其中许多与痕量金属有关。(C)2006爱思唯尔B.V.保留所有权利。
Whether volcanic environments pose a risk in cancer incidence is unknown. We investigated this question in two populations, one from an area with active manifestations of volcanism (Furnas) and another from an area without volcanic activity since 3 million years ago (Santa Maria), both in Azores. Incidence data on cancer among the populations of Furnas and Santa Maria during 1991-2001 were obtained from medical records of local health centers. Age-standardized rates and relative risks were estimated. Overall incidence rates were higher in the volcanically active area when observing all cancers and both sexes combined. However, the non-volcanically active area presented higher rates of cancer of digestive, respiratory and intrathoracic organs, mainly in males, while the area with volcanic manifestations showed higher rates of cancer of lip, oral cavity and pharynx, in both sexes, and female breast. Relative risk estimates between both populations suggest a higher risk for cancer in some groups of organs in Furnas, especially of lip, oral cavity and pharynx cancer, and breast, that may be partially explained by the chronic exposure to environmental factors resulting from volcanic activity, such as hazardous gases and aerosols, much of them associated to trace metals. (c) 2006 Elsevier B.V All rights reserved.