Anesthetic Management of a Pediatric Patient With Pelizaeus-Merzbacher Syndrome: A Case Report
Anesthetic Management of a Pediatric Patient With Pelizaeus-Merzbacher Syndrome: A Case Report
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DOI：
10.1213/xaa.0000000000000826
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发表时间：
2018-12-15
期刊：
影响因子：
0.5
通讯作者：
Kahana, Madelyn
中科院分区：
文献类型：
--
作者：
Patel, Roshan;Kahana, Madelyn
一名3岁的儿童患者，以前诊断为Pelizaeus-Merzbacher综合征，门诊牙科修复。鉴于这种脱髓鞘疾病的罕见性，麻醉计划是针对患者的张力减退和误吸风险，以及尽量减少潜在的并发症，包括癫痫发作，血流动力学不稳定，术后呼吸支持。多模式镇痛，沿着适当的通气策略和正常体温，使患者成功接受全身麻醉，并于当天安全出院回家。
A 3-year-old pediatric patient with previously diagnosed Pelizaeus-Merzbacher syndrome presented for outpatient dental restoration. Given the infrequency of this demyelinating disorder, an anesthetic plan was tailored to address the patient's hypotonia and aspiration risk, as well as minimize potential complications including seizures, hemodynamic instability, and postoperative respiratory support. Multimodal analgesia, along with an appropriate ventilation strategy and normothermia, allowed the patient to successfully undergo a general anesthetic and be safely discharged home the same day.