Performance of screening questionnaires and risk scores for undiagnosed diabetes -: The KORA Survey 2000
Performance of screening questionnaires and risk scores for undiagnosed diabetes -: The KORA Survey 2000
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DOI:
10.1001/archinte.165.4.436
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发表时间:
2005-02-28
影响因子:
--
通讯作者:
Giani, G
中科院分区:
文献类型:
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作者:
Rathmann, W;Martin, S;Giani, G
Background: Validation of published screening questionnaires and risk scores for undiagnosed diabetes has typically not been performed in independent population samples.Methods: Oral glucose tolerance tests were performed in 1353 participants (aged 55-74 years) without known diabetes in the Cooperative Health Research in the Region of Augsburg (KORA) Survey 2000, Augsburg, Germany. Sensitivity, specificity, and the area under the receiver operating characteristic curve (AUC) for undiagnosed diabetes were calculated for various screening questionnaires.Results: Four screening tests (Rotterdam Diabetes Study, Cambridge Risk Score, San Antonio Heart Study, and Finnish Diabetes Risk Score) were applied to the KORA data. The AUCs were 61% (95% confidence interval [ Cl 1, 56%-66%) for the Rotterdam Diabetes Study, 65% (95% Cl, 60%-69%) for the Finnish Diabetes Risk Score (P=. 10 vs Rotterdam), and 67% (95% Cl, 62%-72%) for the Cambridge Risk Score (P