Performance of screening questionnaires and risk scores for undiagnosed diabetes -: The KORA Survey 2000

Performance of screening questionnaires and risk scores for undiagnosed diabetes -: The KORA Survey 2000
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DOI:
10.1001/archinte.165.4.436
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发表时间:
2005-02-28
影响因子:
--
通讯作者:
Giani, G
Giani, G
中科院分区:
其他
文献类型:
--
作者:
Rathmann, W;Martin, S;Giani, G

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背景资料:验证已发表的筛查问卷和未确诊的糖尿病的风险评分通常没有在独立的人群samples.Methods:口服葡萄糖耐量试验进行了1353名参与者(年龄55-74岁),没有已知的糖尿病在合作健康研究在奥格斯堡地区(KORA)调查2000年,奥格斯堡,德国。敏感性,特异性,和未确诊的糖尿病的受试者工作特征曲线(AUC)下的面积计算各种筛选questionnaire.Results:四个筛选测试(鹿特丹糖尿病研究,剑桥风险评分,圣安东尼奥心脏研究,芬兰糖尿病风险评分)被应用到KORA数据。鹿特丹糖尿病研究的AUC为61%(95%置信区间[ Cl 1,56%-66%]),芬兰糖尿病风险评分的AUC为65%(95% CI,60%-69%)(P=. 10 vs鹿特丹),剑桥风险评分为67%(95%CI,62%-72%)(P
Background: Validation of published screening questionnaires and risk scores for undiagnosed diabetes has typically not been performed in independent population samples.Methods: Oral glucose tolerance tests were performed in 1353 participants (aged 55-74 years) without known diabetes in the Cooperative Health Research in the Region of Augsburg (KORA) Survey 2000, Augsburg, Germany. Sensitivity, specificity, and the area under the receiver operating characteristic curve (AUC) for undiagnosed diabetes were calculated for various screening questionnaires.Results: Four screening tests (Rotterdam Diabetes Study, Cambridge Risk Score, San Antonio Heart Study, and Finnish Diabetes Risk Score) were applied to the KORA data. The AUCs were 61% (95% confidence interval [ Cl 1, 56%-66%) for the Rotterdam Diabetes Study, 65% (95% Cl, 60%-69%) for the Finnish Diabetes Risk Score (P=. 10 vs Rotterdam), and 67% (95% Cl, 62%-72%) for the Cambridge Risk Score (P