ALTERATIONS IN MEMBRANE-PERMEABILITY OF MALARIA-INFECTED HUMAN-ERYTHROCYTES ARE RELATED TO THE GROWTH STAGE OF THE PARASITE

ALTERATIONS IN MEMBRANE-PERMEABILITY OF MALARIA-INFECTED HUMAN-ERYTHROCYTES ARE RELATED TO THE GROWTH STAGE OF THE PARASITE
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DOI:
10.1016/0005-2736(82)90178-x
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发表时间:
1982-01-01
期刊:
BIOCHIMICA ET BIOPHYSICA ACTA
影响因子:
--
通讯作者:
CABANTCHIK, ZI
CABANTCHIK, ZI
中科院分区:
其他
文献类型:
--
作者:
KUTNER, S;BARUCH, D;CABANTCHIK, ZI

文献摘要

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Durig the intraerythrocytic growth of Plasmodium falciparum in culture, marked changes are observed in the permeability properties of the host cell membrane. Anionic substances otherwise impermeant to normal cells, become highly permeant to infected cells. These changes become apparent as rings mature into trophozoite and remain throughout schizogony. Permeability changes to anionic substances are not manifested as degradation of band 3, the purported erythrocyte anion transporter. They probably reflect alterations of a more general nature.