Adult-to-adult living-donor liver transplantation: a critical analysis.
Adult-to-adult living-donor liver transplantation: a critical analysis.
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成人对成人活体肝移植：批判性分析。
DOI：
10.1055/s-2000-13153
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发表时间：
2000
期刊：
影响因子：
--
通讯作者：
Busuttil,RW
中科院分区：
文献类型：
--
作者：
Renz,JF;Busuttil,RW
成人对成人活体供体肝移植是增加供体器官供应策略发展的最新成就。该手术的合理性源于器官等待时间的增加、成年移植候选者等待名单上的发病率和死亡率的增加。成人对成人活体供体肝移植的成功应用需要独特的手术、医疗和供体考虑，因为这些手术容易因解剖变异、技术考虑和“部分”移植物的移植而导致独特的并发症。此外，由于供体手术的规模更大，并且可能充满严重的短期和长期发病率以及可能的死亡率，因此利用活体供体进行成人肝移植引起了迄今为止从未遇到过的生物伦理问题。本综述探讨了成人对成人活体肝移植的现状。
Adult-to-adult living-donor liver transplantation is the most recent achievement in the evolution of strategies to increase donor organ supply. Justification of the procedure has evolved from increased organ-waiting times, wait-list morbidity and mortality of adult transplant candidates. Successful application of adult-to-adult living-donor liver transplantation mandates unique surgical, medical, and donor considerations as these procedures predispose to unique complications resulting from anatomic variations, technical considerations, and the transplantation of``partial''grafts. Additionally, because the magnitude of the donor operation is greater and potentially fraught with serious short and long term morbidity and possibly mortality, the utilization of living-donors for adult liver transplantation raises bio-ethical concerns heretofore not encountered. This review explores the current state of adult-to-adult living-donor liver transplantation.