Diagnosis of Mycobacterium bovis infection in cattle by use of the gamma-interferon (Bovigam®) assay
Diagnosis of Mycobacterium bovis infection in cattle by use of the gamma-interferon (Bovigam®) assay
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DOI：
10.1016/j.vetmic.2005.11.029
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发表时间：
2006-02-25
影响因子：
3.3
通讯作者：
Collins, JD
中科院分区：
文献类型：
--
作者：
Gormley, E;Doyle, MB;Collins, JD
γ-干扰素（IFN-γ）检测试剂盒（Bovigam（R））的策略性使用可提供早期鉴定牛分枝杆菌感染牛的方法，从而确保将其从感染牛群中清除。当与结核菌素试验同时使用时，它能够识别受感染的牛，否则直到后来才能检测到，如果有的话。早期发现和清除这些动物可以降低它们成为其他牛感染源的风险。当靶向高流行率畜群时，直接相关畜群所有者的获益可能相当可观，因为该检测试剂盒提供了缩短此类畜群限制期的方法。这有助于使牧群所有者和其他利益攸关方相信，可以根据合理的科学原则制定有效的计划，从受感染的牛群中根除结核病。(c)2005 Elsevier B. V.保留所有权利。
The strategic use of the gamma-interferon (IFN-gamma) assay (Bovigam (R)) can provide a means for the early identification of Mycobacterium bovis infected cattle, thus ensuring their removal from an infected herd. When used in parallel with the tuberculin test, it is capable of identifying infected cattle, which might otherwise not be detected until later, if at all. The early detection and removal of these animals reduces the risk that they will become a source of infection for other cattle. When targeted in herds of high prevalence the benefits to the herd owner directly concerned can be considerable as the assay provides a means of shortening the period of restriction for such herds. This serves to generate confidence among herd owners and other stakeholders that effective schemes, based on sound scientific principles, can be developed to eradicate tuberculosis from infected cattle populations. (c) 2005 Elsevier B.V. All rights reserved.