The pH of Inflammatory Exudates 1
The pH of Inflammatory Exudates 1
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DOI：
10.3181/00379727-137-35782
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发表时间：
1971-09
影响因子：
--
通讯作者：
Donald W. Edlow;W. H. Sheldon
中科院分区：
文献类型：
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作者：
Donald W. Edlow;W. H. Sheldon
总结在不同时间在粘附在正常家兔皮肤伤口上的小腔室中收集炎性渗出物。渗出液pH值与血液pH值进行比较。在每个实验结束时，切除病变进行组织学研究。血液pH值保持不变。渗出液pH值随时间下降，24小时明显下降，72小时最低，96小时无明显变化。细胞渗出在24小时消退，此后仅存在修复过程。明显局限于病变的H-离子浓度的增加发生在炎症的第一个24小时内，并持续在伤口愈合。炎症反应的组织学与渗出液pH值之间的相关性不明显。
Summary Inflammatory exudates were collected at various times in small chambers adhered over skin wounds of normal rabbits. The exudate pH was compared with the blood pH. At termination of each experiment the lesions were excised for histologic study. The blood pH remained unchanged. The pH of the exudate decreased with time showing a definite fall at 24 hr and reaching the lowest value at 72 hr without appreciable further change at 96 hr. The inflammatory cell response in the lesions was slight. Exudation of cells had subsided at 24 hr and thereafter only reparative processes were present. An increase of the H-ion concentration apparently confined to the lesion occurred within the first 24 hr of inflammation and persisted during wound healing. A correlation between the histology of the inflammatory reaction and the pH of the exudate was not apparent.