TUBERCULOSIS - COMMENTARY ON A REEMERGENT KILLER
TUBERCULOSIS - COMMENTARY ON A REEMERGENT KILLER
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DOI：
10.1126/science.257.5073.1055
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发表时间：
1992-08-21
期刊：
影响因子：
56.9
通讯作者：
MURRAY, CJL
中科院分区：
文献类型：
--
作者：
BLOOM, BR;MURRAY, CJL
结核病仍然是世界上死于一种单一传染病的主要原因，尽管人们对其发病机制和预防措施知之甚少。在美国经历了一个世纪的衰落之后，结核病正在增加，出现了对多种抗生素具有抗药性的菌株。病例过多的原因是城市社会结构的变化，人类免疫缺陷病毒的流行，以及某些大城市未能改善公共治疗计划。没有充分解决该国结核病问题的经济代价是从流行病学模型估算出来的。
Tuberculosis remains the leading cause of death in the world from a single infectious disease, although there is little knowledge of the mechanisms of its pathogenesis and protection from it. After a century of decline in the United States, tuberculosis is increasing, and strains resistant to multiple antibiotics have emerged. This excess of cases is attributable to changes in the social structure in cities, the human immunodeficiency virus epidemic, and a failure in certain major cities to improve public treatment programs. The economic costs of not adequately addressing the problem of tuberculosis in this country are estimated from an epidemiological model.