CARIES RISK ASSESSMENT BY A CROSS-SECTIONAL DISCRIMINATION MODEL
CARIES RISK ASSESSMENT BY A CROSS-SECTIONAL DISCRIMINATION MODEL
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DOI：
10.1177/00220345930720021001
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发表时间：
1993-02-01
影响因子：
7.6
通讯作者：
BILLINGS, RJ
中科院分区：
文献类型：
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作者：
LEVERETT, DH;FEATHERSTONE, JDB;BILLINGS, RJ
尽管龋齿的患病率正在持续下降，但它仍然影响着大多数美国人口，并且对于受影响的人来说可能是一个严重的问题。该项目的目标是开发和完善儿童龋齿发病风险评估模型。在本文报道的第一项研究中，确定了一组临床、微生物学、生化和社会人口统计学变量，以可接受的敏感性和特异性水平区分以前没有龋齿经历的儿童和患有高龋齿水平的儿童。总共 313 名儿童（年龄在 12 至 15 岁之间），其中 140 名来自氟化社区，173 名来自缺氟社区，根据之前的龋病经验（零 DMFS 或高 DMFS（含氟社区大于或等于 6 名或缺氟社区大于或等于 8 名））进行选择。进行了 DMFS、氟斑牙和牙菌斑的临床检查。收集受刺激的全唾液用于分析变形链球菌、乳酸杆菌、总活菌群和氟化物浓度。使用调查问卷收集人口统计数据以及有关先前氟化物暴露、饮食习惯和口腔卫生习惯的信息。通过判别分析，使用七个关键的临床和实验室变量，零 DMFS 受试者可以在氟化社区中 77.6% 的病例和缺氟社区中 86.1% 的病例中被正确分类（特异性）。分别有 79.3% 和 88.1% 的病例被归类为高龋对象（敏感性）。
Although the prevalence of dental caries is continuing to decline, it still affects a majority of the US population and can be a serious problem for those afflicted. The objective of this project was to develop and perfect a model for assessment of risk of dental caries onset in children. In the first study, reported herein, a set of clinical, microbiological, biochemical, and socio-demographic variables was identified that distinguished, with an acceptable level of sensitivity and specificity, between children who had no previous caries experience and children who had high caries levels. A total of 313 children-age 12-15 years, 140 from a fluoridated community and 173 from a fluoride-deficient community-was selected on the basis of previous caries experience, either zero DMFS or high DMFS (greater-than-or-equal-to 6 in the fluoridated or greater-than-or-equal-to 8 in the fluoride-deficient community). Clinical exams for DMFS, dental fluorosis, and plaque were conducted. Stimulated whole saliva was collected for analysis of mutans streptococci, lactobacilli, total viable flora, and fluoride concentration. A questionnaire was used for collection of demographic data as well as information on prior fluoride exposure, dietary habits, and oral hygiene practices. By means of discriminant analyses, with use of seven key clinical and laboratory variables, it was possible for zero-DMFS subjects to e classified correctly (specificity) in 77.6% of cases in the fluoridated community and in 86.1% of cases in the fluoride-deficient community. High-caries subjects were classified as such (sensitivity) in 79.3% and 88.1% of cases, respectively.