Circadian expression of NMDA receptor mRNAs, ε3 and ζ1, in the suprachiasmatic nucleus of rat brain
Circadian expression of NMDA receptor mRNAs, ε3 and ζ1, in the suprachiasmatic nucleus of rat brain
复制标题
大鼠脑视交叉上核中 NMDA 受体 mRNA ε3 和 ζ1 的昼夜表达
DOI：
10.1016/0304-3940(94)90488-x
复制
发表时间：
1994
影响因子：
2.5
通讯作者：
M. Mishina
中科院分区：
文献类型：
--
作者：
N. Ishida;M. Matsui;Y. Mitsui;M. Mishina
The presence of the N-methyl-d-aspartate (NMDA) receptor channel subunit ε3 and ζ1 mRNAs in the rat suprachiasmatic nucleus (SCN) was detected by sensitive in situ hybridization. The daily fluctuations in the ε3 and ζ1 subunit mRNAs in their abundance were found in the SCN to be high during the day and lower during the night under 12 h light: 12 h dark conditions (LD 12: 12). Under constant darkness for 15 days, both the ε3 and the ζ1 mRNA levels in the SCN remained cyclic. Furthermore, after exposure of rats to light, the ε3 and ζ1 subunit mRNAs increased during the subjective night, but not during the subjective day. These results implicate the involvement of the ε3 and ζ1 subunits in neuronal signaling in the SCN and suggest that these subunits of the NMDA receptor channel are regulated by light and a circadian clock.
影响因子：
56.9
作者：
GINTY, DD;KORNHAUSER, JM;GREENBERG, ME
通讯作者：
GREENBERG, ME