PET myocardial perfusion imaging in superior vena cava syndrome.
PET myocardial perfusion imaging in superior vena cava syndrome.
复制标题
上腔静脉综合征的 PET 心肌灌注成像。
DOI：
10.1007/s12350-022-03033-1
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Osborne,MichaelT
中科院分区：
文献类型：
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作者：
Mezue,Kenechukwu;Chow,David;Tawakol,Ahmed;Fakhri,GeorgesEl;Osborne,MichaelT
上腔静脉（SVC）综合征是由SVC阻塞引起的一系列临床表现，通常是由于恶性肿瘤或中心静脉导管和起搏器/除颤器导联导致的SVC狭窄。SVC综合征通过静脉侧支将血液分流至右心房，从而影响循环血流动力学。这种较长的循环时间可能会影响使用正电子发射断层扫描(PET)/计算机断层扫描进行的心肌灌注成像（MPI）的心肌血流测量，因为示踪剂的流动和摄取动力学是基于全身血流通畅的假设。我们报告一例伴有SVC综合征和PET MPI异常的患者。
Superior vena cava (SVC) syndrome is the constellation of clinical findings resulting from SVC occlusion, commonly due to malignancy or SVC stenosis consequent to central venous catheters and pacemaker/defibrillator leads. 1 SVC syndrome affects circulatory hemodynamics by diverting blood to the right atrium through venous collaterals. This longer circulation time could affect myocardial blood flow measurements on myocardial perfusion imaging (MPI) with positron emission tomography (PET)/computed tomography, as the kinetics of tracer flow and uptake are based on an assumption of unobstructed systemic blood flow. 2 We report a case of a patient with SVC syndrome and abnormal PET MPI.