A Neglected Case of Multifocal Liposarcoma Presented in Five Different Sites in a Syrian Woman: A case report
A Neglected Case of Multifocal Liposarcoma Presented in Five Different Sites in a Syrian Woman: A case report
复制标题
叙利亚妇女五个不同部位出现的多灶性脂肪肉瘤被忽视的病例：病例报告
DOI：
10.1016/j.ijscr.2019.10.077
复制
发表时间：
2019
影响因子：
0.6
通讯作者：
R. Masri
中科院分区：
文献类型：
--
作者：
Ieman Alawad;Ahmad Al;Ahmad Ghazal;A. Ibrahim;R. Masri
多灶性软组织肉瘤是一种罕见的临床实体，发生于四肢软组织肉瘤患者的1%和脂肪肉瘤患者的4.5%。多灶性疾病可能同时或异时出现，并已与预后差。病例介绍在此，我们报告了一个罕见的情况下，叙利亚妇女患者与六个不同的脂肪肉瘤病灶在五个网站在diagnosis. Discussion脂肪肉瘤目前分为四个不同的亚型根据组织学或遗传学分析，根据世界卫生组织（WHO），包括细胞分化，去分化粘液状多形性在目前的工作中，我们报告了一个被忽视的病人与多中心圆细胞脂肪肉瘤在五个不同的sites.ConclusionMedicine不能提供太多的照顾，这些先进的情况下，多中心脂肪肉瘤到目前为止。因此，应该进行更多的研究，以提高管理这些实体的能力，并确定潜在的新疗法。
IntroductionMultifocal soft tissue sarcoma is a rare clinical entity occurring in 1 % of patients with extremity soft tissue sarcoma and in 4.5 % of patients with liposarcoma. Multifocal disease may arise either synchronously or metachronously and has been associated with poor prognosis.Case presentationHerein, we report a rare case of a Syrian woman patient with six different foci of liposarcoma in five sites at the time of diagnosis.DiscussionLiposarcomas are currently classified into four different subtypes based on histologic or genetic analysis according to the World Health Organization (WHO), including cell-differentiated, dedifferentiated, myxoid, and pleomorphic. In the present work, we report a neglected patient with a multicentric round cell liposarcoma in five different sites.ConclusionMedicine cannot provide much care for these advanced cases of multicentric liposarcoma so far. Therefore, more research should be conducted to improve the ability to manage these entities and to identify potential novel therapies.