Thyroid carcinoma and thyroiditis in an endemic goitre region before and after iodine prophylaxis.
Thyroid carcinoma and thyroiditis in an endemic goitre region before and after iodine prophylaxis.
复制标题
地方性甲状腺肿地区碘预防前后的甲状腺癌和甲状腺炎。
DOI：
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发表时间：
1985
期刊：
影响因子：
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通讯作者：
E. Williams
中科院分区：
文献类型：
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作者：
H. R. Harach;D. Escalante;A. Oñativia;J. Outes;E. Day;E. Williams
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Iodine prophylaxis was introduced to the moderately severe goitre endemic area in Salta, Argentina, in 1963. All thyroidectomies from a 20 year period were reviewed, and 148 thyroid malignancies carefully studied. The period from 5 to 15 years after iodization was associated with a lower frequency of follicular carcinomas and a higher frequency of papillary carcinomas than the period before and up to 5 years after prophylaxis. Lymphoid infiltration in the non-tumorous thyroid was relatively infrequent before iodine prophylaxis: it was much higher in each of the post-prophylaxis periods. These results, in agreement with other studies, support the view that an increased iodine intake is associated with an increased incidence of papillary carcinoma of the thyroid and thyroiditis.