WebACT - an online companion for the artemis comparison tool
WebACT - an online companion for the artemis comparison tool
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DOI：
10.1093/bioinformatics/bti601
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发表时间：
2005-09-15
期刊：
影响因子：
5.8
通讯作者：
Spratt, BG
中科院分区：
文献类型：
--
作者：
Abbott, JC;Aanensen, DM;Spratt, BG
WebACT是一种在线资源，能够快速提供多达五个基因组序列之间的同步BLAST比较，其格式适合于使用众所周知的Artemis比较工具（ACT）进行可视化。可以使用通过EMBL数据库查询直接检索的序列或通过输入或上传用户序列实时生成比较。此外，预先计算的比较，所有公开可用的，完整的原核基因组和质粒目前包含在基因组评论数据库（372个序列，代表175个不同的物种）。该系统旨在最大限度地减少下载的数据量并最大限度地提高性能。基因组序列、注释和预先计算的比较被存储在关系数据库中，允许基于用户定义的序列区域的灵活查询，从整个基因组到特定基因侧翼的定义区域。比较和序列文件，无论是在线计算的还是从预先计算的基因组比较数据库中检索的，都可以使用ACT在线查看并可供下载。
WebACT is an online resource which enables the rapid provision of simultaneous BLAST comparisons between up to five genomic sequences in a format amenable for visualization with the well-known Artemis Comparison Tool (ACT). Comparisons can be generated on-the-fly using sequences directly retrieved via EMBL database queries, or by entering or uploading user sequences. Furthermore, pre-computed comparisons are available between all publicly available, completed prokaryotic genomes and plasmids currently contained within the Genome Reviews database (372 sequences, representing 175 different species). The system is designed to minimize the volume of downloaded data and maximize performance. Genome sequences, annotation and pre-computed comparisons are stored in a relational database allowing flexible querying based on user-defined sequence regions, from whole genome to a defined region flanking a specified gene. Comparison and sequence files, whether computed online or retrieved from the database of pre-computed genome comparisons, can be viewed online using ACT and are available for download.