COX-1 and COX-2 expression in feline oral squamous cell carcinoma
COX-1 and COX-2 expression in feline oral squamous cell carcinoma
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DOI：
10.1016/j.jcpa.2006.06.001
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发表时间：
2006-08-01
影响因子：
0.8
通讯作者：
Adams, V.
中科院分区：
文献类型：
--
作者：
Hayes, A.;Scase, T.;Adams, V.
本研究通过免疫组织化学方法证明了猫口腔鳞状细胞癌 (FOSCC) 中环氧合酶-1 (COX-1) 和环氧合酶-2 (COX-2) 的表达，并针对人类表位产生了原代多克隆抗体。 COX-2 免疫标记位于细胞质内，在某些肿瘤细胞中位于核周；它以小比例被证明（
This study demonstrated immunohistochemically the expression of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) in feline oral squamous cell carcinoma (FOSCC), with primary polyclonal antibodies raised against human epitopes. COX-2 immunolabelling was intracytoplasmic and, in some neoplastic cells, perinuclear; it was demonstrated in a small proportion (