Overcoming barriers to prevention, care, and treatment of hepatitis C in illicit drug users
Overcoming barriers to prevention, care, and treatment of hepatitis C in illicit drug users
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DOI：
10.1086/427441
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发表时间：
2005-04-15
影响因子：
11.8
通讯作者：
Cargill, VA
中科院分区：
文献类型：
--
作者：
Edlin, BR;Kresina, TF;Cargill, VA
在美国和其他发达国家，注射吸毒是导致丙型肝炎病毒（HCV）感染的大部分原因。HCV感染是注射吸毒者（IDUs）的一种复杂且具有挑战性的医疗状况。治疗非法吸毒者丙型肝炎的要素包括预防咨询和教育;筛查传播风险行为;检测HCV和人类免疫缺陷病毒感染;接种甲型和B型肝炎病毒疫苗;评估合并症;协调药物滥用治疗服务、精神病护理和社会支持;评估肝病;以及HCV感染的干扰素治疗。照顾使用非法药物的患者对卫生保健团队提出了挑战，需要耐心、经验和对药物使用和成瘾动态的理解。尽管如此，方案正在成功地将注射吸毒者的丙型肝炎护理纳入卫生保健环境，包括初级保健、美沙酮治疗和其他药物滥用治疗方案、传染病诊所和教养所诊所。
Injection drug use accounts for most of the incident infections with hepatitis C virus (HCV) in the United States and other developed countries. HCV infection is a complex and challenging medical condition in injection drug users (IDUs). Elements of care for hepatitis C in illicit drug users include prevention counseling and education; screening for transmission risk behavior; testing for HCV and human immunodeficiency virus infection; vaccination against hepatitis A and B viruses; evaluation for comorbidities; coordination of substance abuse treatment services, psychiatric care, and social support; evaluation of liver disease; and interferon-based treatment for HCV infection. Caring for patients who use illicit drugs presents challenges to the health-care team that require patience, experience, and an understanding of the dynamics of substance use and addiction. Nonetheless, programs are successfully integrating hepatitis C care for IDUs into health-care settings, including primary care, methadone treatment and other substance-abuse treatment programs, infectious disease clinics, and clinics in correctional facilities.