A Y chromosome census of the British Isles
A Y chromosome census of the British Isles
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DOI：
10.1016/s0960-9822(03)00373-7
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发表时间：
2003-05-27
期刊：
影响因子：
9.2
通讯作者：
Goldstein, DB
中科院分区：
文献类型：
--
作者：
Capelli, C;Redhead, N;Goldstein, DB
不列颠群岛的人口更替程度与文化变迁有关，这一点一直受到广泛的争论[1-3]。最近的研究表明，对不列颠群岛和欧洲大陆的遗传变异进行比较，可以阐明不列颠群岛历史上的特定人口统计过程。例如，Wilson等人[4]使用巴斯克人和凯尔特人Y染色体的相似性来论证这些人群从旧石器时代晚期到现在的父系历史的遗传连续性（另见[5]）。这些群体Y染色体组成的差异也表明了挪威对苏格兰大陆北部奥克尼群岛的影响的遗传特征，奥克尼群岛是公元800年至1300年期间维京海盗活动的重要中心。最近，Weale等人[7]根据对横跨英格兰和威尔士的东西向样带收集的8个英国样本集的分析，认为大量盎格鲁-撒克逊男性迁移到英格兰中部。为了提供一个更完整的评估父系遗传史的不列颠群岛，我们比较了Y染色体组成的多个地理上遥远的英国样本集与收藏品从挪威（两个网站），丹麦，和德国和收藏品从中部爱尔兰，分别代表，假定的入侵和土著人口。通过分析来自25个主要是小城市的1772条Y染色体，我们发现不列颠群岛的不同地区有着截然不同的父系历史;人口更替和遗传连续性的程度显示了整个采样地区的系统性变化。
The degree of population replacement in the British Isles associated with cultural changes has been extensively debated [1-3]. Recent work has demonstrated that comparisons of genetic variation in the British Isles and on the European Continent can illuminate specific demographic processes in the history of the British Isles. For example, Wilson et al. [4] used the similarity of Basque and Celtic Y chromosomes to argue for genetic continuity from the Upper Palaeolithic to the present in the paternal history of these populations (see also [5]). Differences in the Y chromosome composition of these groups also suggested genetic signatures of Norwegian influence in the Orkney Islands north of the Scottish mainland, an important center of Viking activities between 800 and 1300 A.D. [6]. More recently, Weale et al. [7] argued for substantial Anglo-Saxon male migration into central England based on the analysis of eight British sample sets collected on an east-west transect across England and Wales. To provide a more complete assessment of the paternal genetic history of the British Isles, we have compared the Y chromosome composition of multiple geographically distant British sample sets with collections from Norway (two sites), Denmark, and Germany and with collections from central Ireland, representing, respectively, the putative invading and the indigenous populations. By analyzing 1772 Y chromosomes from 25 predominantly small urban locations, we found that different parts of the British Isles have sharply different paternal histories; the degree of population replacement and genetic continuity shows systematic variation across the sampled areas.