A new method for estimating the effective population size from allele frequency changes.
A new method for estimating the effective population size from allele frequency changes.
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DOI：
10.1093/genetics/104.3.531
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发表时间：
1983-07
期刊：
影响因子：
3.3
通讯作者：
E. Pollak
中科院分区：
文献类型：
--
作者：
E. Pollak
一个新的程序提出了估计有效的人口规模，给定的信息是可用的等位基因在一个或多个独立的分离位点的频率变化和人口观察在两个或多个单独的时间。近似表达式获得的方差的新的统计量，以及其他人，也基于等位基因频率的变化，已在文献中讨论。该分析表明，新统计量通常具有比其他统计量更小的方差。估计的有效人口规模和估计的标准误差计算的两个苍蝇种群的数据，已在较早的文件中讨论。在这两种情况下，有证据表明，有效人口规模远远小于人口普查的最低人口规模。
A new procedure is proposed for estimating the effective population size, given that information is available on changes in frequencies of the alleles at one or more independently segregating loci and the population is observed at two or more separate times. Approximate expressions are obtained for the variances of the new statistic, as well as others, also based on allele frequency changes, that have been discussed in the literature. This analysis indicates that the new statistic will generally have a smaller variance than the others. Estimates of effective population sizes and of the standard errors of the estimates are computed for data on two fly populations that have been discussed in earlier papers. In both cases, there is evidence that the effective population size is very much smaller than the minimum census size of the population.