Project ice storm: Prenatal maternal stress affects cognitive and linguistic functioning in 51/2-year-old children
Project ice storm: Prenatal maternal stress affects cognitive and linguistic functioning in 51/2-year-old children
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DOI：
10.1097/chi.0b013e31817eec80
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发表时间：
2008-09-01
影响因子：
13.3
通讯作者：
King, Suzanne
中科院分区：
文献类型：
--
作者：
Laplante, David P.;Brunet, Alain;King, Suzanne
目的：这是一项前瞻性研究，旨在确定自然灾害导致的产前母亲压力暴露程度在多大程度上解释了后代在51岁半时智力和语言表现的差异，同时控制了几个潜在的混杂变量。方法：研究对象是89名51岁的孩子，他们的母亲在一次自然灾害中怀孕：1998年1月发生在加拿大魁北克省的冰暴危机导致300万人停电长达40天。在1998年6月，妇女们完成了几份问卷，包括客观压力程度（Storm32）和主观痛苦程度（事件影响量表-修订）。他们的孩子在5岁半时接受韦氏学前和小学智力修正量表（IQ）和皮博迪图片词汇测试（语言）的评估，母亲完成了最近生活事件和心理功能的评估。结果：在子宫内暴露于高水平客观压力下的儿童，与暴露于低水平或中等水平客观产前母亲压力下的儿童相比，具有较低的全面智商、言语智商和语言能力；主观压力和客观压力对绩效智商没有影响。趋势分析表明，除分组设计外，所有结果变量在客观应激和功能之间存在显著的曲线关联。结论：产前暴露于中度严重的自然灾害与51岁半时较低的认知和语言能力有关。
Objective: This was a prospective study designed to determine the extent to which the degree of exposure to prenatal maternal stress due to a natural disaster explains variance in the intellectual and language performance of offspring at age 51/2 while controlling for several potential confounding variables. Method: Subjects were eightynine 51/2-year-old children whose mothers were pregnant during a natural disaster: the January 1998 ice storm crisis in the Canadian province of Quebec that resulted in power losses for 3 million people for as long as 40 days. In June 1998, women completed several questionnaires including those about the extent of objective stress (Storm32) and subjective distress (impact of Events Scale-Revised) experienced due to the storm. Their children were assessed with the Wechsler Preschool and Primary Scale of Intelligence-Revised (IQ) and Peabody Picture Vocabulary Test-Revised (language) at 51/2 years of age, and mothers completed assessments of recent life events and psychological functioning. Results: Children exposed in utero to high levels of objective stress had lower Full Scale IQs, Verbal IQs, and language abilities compared to children exposed to low or moderate levels of objective prenatal maternal stress; there were no effects of subjective stress or objective stress on Performance IQs. Trend analyses show that for all outcome variables except Block Design, there was a significant curvilinear association between objective stress and functioning. Conclusions: Prenatal exposure to a moderately severe natural disaster is associated with lower cognitive and language abilities at 51/2 years of age.