Development of a practicable non-contact bedside autonomic activation monitoring system using microwave radars and its clinical application in elderly people
Development of a practicable non-contact bedside autonomic activation monitoring system using microwave radars and its clinical application in elderly people
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DOI：
10.1007/s10877-013-9448-3
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发表时间：
2013-06-01
影响因子：
2.2
通讯作者：
Kurita, Akira
中科院分区：
文献类型：
--
作者：
Matsui, Takemi;Yoshida, Yuto;Kurita, Akira
我们开发了一种实用的，非接触式，自主激活监测系统，使用微波雷达，不会对被监测个体施加任何压力。近年来，老龄化人口的迅速增加引起了发达国家的关注。因此，医院和护理机构需要对老年患者进行长期健康监测。该系统可以监测由糖尿病或心肌梗塞（MI）等慢性疾病引起的老年人自主神经功能障碍，同时以非接触方式测量生命体征。该系统通过安装在床垫下面的双24ghz紧凑型微波雷达测量老年人躺在床上的心率变异性（HRV）。心率参数（LF、HF和LF/HF）由心脏峰至峰间隔确定，由雷达采用最大熵法检测。我们从晚上7点到早上6点在东京一家特殊的养老院对15名有或没有糖尿病或心肌梗塞的老年人（72-99岁）进行了系统测试。系统测得的LF/HF与动态心电图（Holter electrocardiography， ECG）具有显著相关性（R = 0.89, p < 0.01）。糖尿病组LF （radar）低于非糖尿病组（糖尿病组119.8 +/- A 57.8，非糖尿病组405.9 +/- A 112.6, p < 0.01）。心肌梗死后的HF （radar）显著低于非心肌梗死组（心肌梗死后为219.7 +/- A 131.7，非心肌梗死组为580.0 +/- A 654.6, p < 0.05）。以往使用常规心电图的研究表明，糖尿病性神经病变使LF降低，心肌梗死引起副交感神经衰减导致HF降低。我们的研究表明，心肌梗死后患者的平均SDNN小于50 ms，这是已知的高死亡率。非接触式自主激活监测系统允许长期健康管理，特别是在睡眠时间的老年人在医疗机构。
We developed a practicable, non-contact, autonomic activation monitoring system using microwave radars without imposing any stress on monitored individuals. Recently, the rapid increase in the aging population has raised concerns in developed countries. Thus, hospitals and care facilities will need to perform long-term health monitoring of elderly patients. The system allows monitoring of geriatric autonomic dysfunctions caused by chronic diseases, such as diabetes or myocardial infarction (MI), while measuring vital signs in non-contact way. The system measures heart rate variability (HRV) of elderly people in bed using dual, 24-GHz, compact microwave radars attached beneath the bed mattress. HRV parameters (LF, HF, and LF/HF) were determined from the cardiac peak-to-peak intervals, which were detected by radars using the maximum entropy method. We tested the system on 15 elderly people with and without diabetes or MI (72-99 years old) from 7:00 p.m. to 6:00 a.m. at a special nursing home in Tokyo. LF/HF obtained by the system correlated significantly (R = 0.89; p < 0.01) with those obtained by Holter electrocardiography (ECG). Diabetic subjects showed significantly lower LF (radar) than non-diabetic (119.8 +/- A 57.8 for diabetic, 405.9 +/- A 112.6 for non-diabetic, p < 0.01). HF (radar) of post-MI subjects was significantly lower than that of non-MI (219.7 +/- A 131.7 for post-MI and 580.0 +/- A 654.6 for non-MI, p < 0.05). Previous studies using conventional ECG reveal that diabetic neuropathy decreases LF, and also MI causes parasympathetic attenuation which leads to HF reduction. Our study showed that average SDNN of post-MI patients is smaller than 50 ms which is known to have high mortality. The non-contact autonomic activation monitoring system allows a long-term health management especially during sleeping hours for elderly people at healthcare facilities.