Indices of multilocus linkage disequilibrium

Indices of multilocus linkage disequilibrium
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DOI:
10.1046/j.1471-8278.2000.00014.x
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发表时间:
2001-03-01
期刊:
MOLECULAR ECOLOGY NOTES
影响因子:
--
通讯作者:
Burt, A
Burt, A
中科院分区:
其他
文献类型:
--
作者:
Agapow, PM;Burt, A

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连锁不平衡是一种普遍存在的生物学现象。然而,不平衡的一个常见度量-关联指数或I-A -取决于样本大小。在本文中,我们提出了一个修改的I-A,消除这种依赖性。该方法已在软件包中实现。
Linkage disequilibrium is an ubiquitous biological phenomenon. However a common metric for disequilibrium - the index of association or I-A - is dependent on sample size. In this paper we present a modification of I-A that removes this dependency. This method has been implemented in a software package.