Reciprocal DNA nanomechanical devices controlled by the same set strands.
Reciprocal DNA nanomechanical devices controlled by the same set strands.
复制标题
由同一组链控制的相互 DNA 纳米机械装置。
DOI：
10.1021/nl901008k
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发表时间：
2009
期刊：
影响因子：
10.8
通讯作者：
Seeman,NadrianC
中科院分区：
文献类型：
--
作者：
Liu,Chunhua;Jonoska,Natasha;Seeman,NadrianC
往复装置是宏观机械的关键特征。我们已经将DNA px - jx2设备调整为互惠格式。PX- jx2设备是一个健壮的依赖于序列的纳米机器，其状态由一对控制链建立，控制链将其设置为PX状态或jx2状态。这两种状态的不同之处在于它们的两端旋转了半圈。在这里，我们报告了一对相互的PX- jx2器件的构造，其中导致一个器件的PX状态的控制链导致另一个器件的jx2状态，反之亦然。用凝胶电泳和原子力显微镜证实了这两种器件体系的形成、转变和相互运动。该系统可能用于分子机器人应用，其中互反运动除了对分子编排和分子美学的固有贡献外，还具有价值。
Reciprocating devices are key features in macroscopic machines. We have adapted the DNA PX-JX2device to a reciprocal format. The PX-JX2device is a robust sequence-dependent nanomachine, whose state is established by a pair of control strands that set it to be either in the PX state or in the JX2state. The two states differ by a half-turn rotation between their ends. Here we report the construction of a pair of reciprocal PX-JX2devices, wherein the control strands leading to the PX state in one device lead to the JX2state in the other device and vice versa. The formation, transformation, and reciprocal motions of these two device systems are confirmed using gel electrophoresis and atomic force microscopy. This system is likely to be of use for molecular robotic applications where reciprocal motions are of value in addition its inherent contribution to molecular choreography and molecular aesthetics.