Extradural Contralateral Ventral Root Transfer to Treat Lower Limb Motor Dysfunction in Paraplegia
Extradural Contralateral Ventral Root Transfer to Treat Lower Limb Motor Dysfunction in Paraplegia
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硬膜外对侧腹根移植治疗截瘫下肢运动功能障碍
DOI：
10.1097/brs.0000000000004373
复制
发表时间：
2022-07
期刊：
影响因子：
--
通讯作者：
Tao Sui
中科院分区：
文献类型：
--
作者：
Jie Chang;Jiang Cao;Chaoqin Wu;Sheng Zhang;Binyu Wang;Xiaojian Cao;Tao Sui
本研究以8具身体为研究对象，探讨了将对侧T11腹根硬膜外移位至同侧L2平面，将对侧L1腹根硬膜外移位至同侧L3平面以恢复截瘫患者肢体功能的解剖学可行性。到目前为止，与上肢功能障碍不同的是，关于手术治疗下肢运动功能障碍的研究很少。本研究包括8具身体，以证实神经移位的可行性。分离各节段的VR和背根后，将T11和L1节段的VRS分别与L2和L3的VRS吻合。测量供体神经根VRS的长度和供受体神经之间的距离。H&E染色以确定VRS的轴突数目和横截面积。用60例健康成人腰椎X线片测量供受神经之间的距离，暴露双侧硬膜外各根后，即可将VRS与全根分离。T11和L2、L1和L3的VRS之间的距离明显大于供神经的长度。因此，采用腓肠神经移植。对60名健康成年人的腰椎X光片的测量证实了这一结果。本研究证实了偏瘫患者将T11至L2和L1至L3的VRS移位以恢复肢体功能的解剖学可行性。
Eight cadavers were included in this anatomical study.This study aimed to confirm the anatomical feasibility of extradural transfer of the contralateral T11 ventral root (VR) to the ipsilateral L2 level and the contralateral L1 VR to the ipsilateral L3 level to restore lower limb function in cases of paraplegia.Motor dysfunction due to hemiplegia significantly affects the daily life of patients. To date, unlike in cases of upper limb dysfunction, there are few studies on the surgical management of lower limb movement dysfunction.Eight cadavers were included in this study to confirm the feasibility of the nerve transfer. After separating the VR and dorsal root (DR) at each level, the VRs at the T11 and L1 levels were anastomosed with the VRs of L2 and L3, respectively. The length of the VRs of donor roots and the distance between the donor and recipient nerves were measured. H&E staining was performed to verify the number of axons and the cross-sectional area of the VRs. Lumbar X-rays of 60 healthy adults were used to measure the distance between the donor and recipient nerves.After exposing the bilateral extradural each root, the VRs could be easily isolated from the whole root. The distance between the VRs of T11 and L2, L1 and L3 was significantly longer than the length of the donor nerve. Therefore, the sural nerve was used for grafting. The measurements performed on the lumbar X-rays of the 60 healthy adults confirmed the results. The number of axons and cross-sectional area of the VRs were measured.Our study confirmed the anatomical feasibility of transferring the VRs of T11 to L2 and that of L1 to L3 to restore lower limb function in cases of hemiplegia.5.
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DOI：
10.1016/s0003-9993(95)80038-7
发表时间：
1995-01-01
影响因子：
4.3
作者：
JORGENSEN, HS;NAKAYAMA, H;OLSEN, TS
通讯作者：
OLSEN, TS
脊髓损伤膀胱神经重建的硬膜外神经吻合技术在人体尸体中的解剖可行性研究
影响因子：
3
作者：
Zhou Xiaoji;Liu Yongtao;Ma Jun;Sui Tao;Ge Yingbin;Cao Xiaojian
通讯作者：
Cao Xiaojian
影响因子：
3.9
作者：
Mihai EE;Dumitru L;Mihai IV;Berteanu M
通讯作者：
Berteanu M
硬膜外神经根移植在脊髓损伤下肢功能恢复中的应用：假设和尸体可行性研究。
DOI：
10.1097/brs.0000000000004013
发表时间：
2021
期刊：
Spine (Phila Pa 1976)
影响因子：
--
作者：
Hongtao Chen;Jiang Cao;Sheng Zhang;Tao Sui;Kaixiang Yang;Xiaojian Cao
通讯作者：
Xiaojian Cao
影响因子：
--
作者：
Luque-Moreno C;Ferragut-Garcías A;Rodríguez-Blanco C;Heredia-Rizo AM;Oliva-Pascual-Vaca J;Kiper P;Oliva-Pascual-Vaca Á
通讯作者：
Oliva-Pascual-Vaca Á