HUMAN INFECTION WITH CRYPTOSPORIDIUM SPP - RESULTS OF A 24-MONTH SURVEY

HUMAN INFECTION WITH CRYPTOSPORIDIUM SPP - RESULTS OF A 24-MONTH SURVEY
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DOI:
10.5694/j.1326-5377.1987.tb133350.x
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发表时间:
1987-08-17
影响因子:
11.4
通讯作者:
DWYER, B
DWYER, B
中科院分区:
医学2区
文献类型:
--
作者:
BIGGS, BA;MEGNA, R;DWYER, B

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我们报告的结果,为期两年的调查粪便标本的原生动物病原体,隐孢子虫。在2248名接受检测的患者中,发现55名(2.5%)患者患有隐孢子虫感染。寄生虫的传播似乎主要发生在人与人之间。在免疫功能正常的患者中,它会引起急性,有时甚至是严重的胃肠炎。免疫功能不全的患者经历了一种可变的疾病,从无症状携带到严重腹泻,导致吸收不良,最终死亡。隐孢子虫是引起胃肠炎的重要原因,也可能是获得性免疫缺陷综合征的主要特征。因此,在所有急性腹泻患者中筛查该病原体是相关的。
We report the findings of a two-year survey of faecal specimens for the protozoal pathogen, Cryptosporidium. Of the 2248 patients who were tested, 55 (2.5%) patients were found to have cryptosporidial infection. Transmission of the parasite appeared mainly to occur from person to person. In immunocompetent patients it caused an acute and sometimes severe gastroenteritis. Immunoincompetent patients experienced a variable illness that ranged from asymptomatic carriage to severe diarrhoea, causing malabsorption and ultimately death. Cryptosporidium is an important cause of gastroenteritis and may be the presenting feature of the acquired immunodeficiency syndrome. Therefore, it is pertinent to screen for this pathogen in all patients with acute diarrhoea.