Cancer-related fatigue in patients attending oncological rehabilitation programs: Prevalence, patterns and predictors
Cancer-related fatigue in patients attending oncological rehabilitation programs: Prevalence, patterns and predictors
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DOI：
10.1159/000069864
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发表时间：
2003-02-01
期刊：
影响因子：
0.3
通讯作者：
Moser, MT
中科院分区：
文献类型：
--
作者：
Bartsch, HH;Weis, J;Moser, MT
背景：疲劳是癌症患者最常见的症状之一。这是医疗和心理社会康复方案的目标，以减少身体损伤和心理社会痛苦。关于参加此类康复计划的患者的疲劳感的患病率或模式，目前还没有可靠的数据。因此，我们开始了一项横断面研究，以评估这一现象。患者和方法：采用EORTC QLQ-C30、HADS和MFI问卷对144例不同恶性肿瘤患者的疲劳感的发生率、类型和治疗的必要性进行评估。结果：1/3的患者被诊断为乳腺癌，27%的患者患有胃肠癌，20%的患者患有血液/淋巴疾病。3种仪器的疲劳程度之间有很好的相关性。22%的患者表现出明显的疲劳症状。单变量分析没有反映出疲劳的严重程度在诊断、血红蛋白水平、病史和治疗史或社会人口学数据方面的任何显著差异。然而，使用聚类分析，我们可以识别出三组在疲劳和生活质量测量方面有显著差异的患者。结论：我们从我们的数据中得出结论，疲劳是参加医疗和心理康复计划的癌症患者的一个重要现象。这对这些患者重新融入日常生活的能力和程度产生了影响。
Background: Fatigue is one of the most frequent symptoms in cancer patients. It is the aim of medical and psychosocial rehabilitation programs to reduce physical impairments and psychosocial distress. There are no reliable data on the prevalence or the pattern of fatigue in patients attending such rehabilitation programs. We therefore initiated a cross-sectional study to evaluate this phenomenon. Patients and Methods: Using the EORTC QLQ-C30, HADS and MFI questionnaires in 144 patients with different malignant diseases the incidence, patterns and necessity of treatment of fatigue were evaluated. Results: One third of the patients were diagnosed with breast cancer, 27% with gastrointestinal cancers and 20% suffered from haematologic/lymphatic diseases. There was a good correlation between fatigue levels in the 3 instruments used. 22% of all patients showed significant symptoms of fatigue. The univariate analysis did not reflect any significant differences in severity of fatigue with respect to diagnosis, haemoglobin levels, medical and therapeutic history or sociodemographic data. However, using cluster analysis we could identify 3 groups of patients that differ significantly in fatigue and quality-of-life measurements. Conclusion: We conclude from our data that fatigue is an important phenomenon in cancer patients who attend medical and psychosocial rehabilitation programs. This has an impact on the ability and degree to reintegrate these patients into everyday life.