An open-source tool for longitudinal whole-brain and white matter lesion segmentation.
An open-source tool for longitudinal whole-brain and white matter lesion segmentation.
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DOI：
10.1016/j.nicl.2023.103354
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发表时间：
2023
影响因子：
4.2
通讯作者：
Van Leemput, Koen
中科院分区：
文献类型：
--
作者：
Cerri, Stefano;Greve, Douglas N.;Hoopes, Andrew;Lundell, Henrik;Siebner, Hartwig R.;Muehlau, Mark;Van Leemput, Koen
关键词：
一种纵向MRI扫描的全脑分割方法。该方法适用于不同的扫描仪和MRI序列。它不会对后续扫描的数量或时间施加任何限制。它还可以同时分割白质病变。该方法是作为freesurfer的一部分公开提供的。在本文中，我们描述并验证了一种用于纵向MRI扫描的全脑分割的纵向方法。它建立在现有的全脑分割方法的基础上，该方法可以处理多对比度数据并稳健地分析带有白质病变的图像。这种方法在这里扩展了特定于对象的潜在变量，这些变量鼓励其分割结果之间的时间一致性，使其能够更好地跟踪数十个神经解剖结构和白质病变中的细微形态变化。我们在控制对象和阿尔茨海默病和多发性硬化症患者的多个数据集上验证了该方法，并将其结果与其原始横截面公式和两种基准纵向方法的结果进行了比较。结果表明，该方法达到了较高的重测信度，同时对纵向疾病效应的组间差异更加敏感。一个实现是作为开源神经成像包freesurfer的一部分公开提供的。
A method for whole-brain segmentation of longitudinal MRI scans. The method is adaptive to different scanners and MRI sequences. It does not put any constraints on the number or the timing of follow-up scans. It can also segment white matter lesions simultaneously. The method is publicly available as part of FreeSurfer. In this paper we describe and validate a longitudinal method for whole-brain segmentation of longitudinal MRI scans. It builds upon an existing whole-brain segmentation method that can handle multi-contrast data and robustly analyze images with white matter lesions. This method is here extended with subject-specific latent variables that encourage temporal consistency between its segmentation results, enabling it to better track subtle morphological changes in dozens of neuroanatomical structures and white matter lesions. We validate the proposed method on multiple datasets of control subjects and patients suffering from Alzheimer’s disease and multiple sclerosis, and compare its results against those obtained with its original cross-sectional formulation and two benchmark longitudinal methods. The results indicate that the method attains a higher test–retest reliability, while being more sensitive to longitudinal disease effect differences between patient groups. An implementation is publicly available as part of the open-source neuroimaging package FreeSurfer.
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影响因子：
3.7
作者：
Wang L;Shi F;Li G;Shen D
通讯作者：
Shen D
影响因子：
4.4
作者：
Battaglini, Marco;Rossi, Francesca;De Stefano, Nicola
通讯作者：
De Stefano, Nicola
影响因子：
29
作者：
Cagol, Alessandro;Schaedelin, Sabine;Granziera, Cristina
通讯作者：
Granziera, Cristina
影响因子：
9.9
作者：
Edmonds, Emily C.;Weigand, Alexandra J.;McDonald, Carrie R.
通讯作者：
McDonald, Carrie R.
多发性硬化症中区域灰质萎缩的进展。
DOI：
10.1093/brain/awy088
发表时间：
2018-06-01
期刊：
Brain : a journal of neurology
影响因子：
--
作者：
Eshaghi A;Marinescu RV;Young AL;Firth NC;Prados F;Jorge Cardoso M;Tur C;De Angelis F;Cawley N;Brownlee WJ;De Stefano N;Laura Stromillo M;Battaglini M;Ruggieri S;Gasperini C;Filippi M;Rocca MA;Rovira A;Sastre-Garriga J;Geurts JJG;Vrenken H;Wottschel V;Leurs CE;Uitdehaag B;Pirpamer L;Enzinger C;Ourselin S;Gandini Wheeler-Kingshott CA;Chard D;Thompson AJ;Barkhof F;Alexander DC;Ciccarelli O
通讯作者：
Ciccarelli O