Missed diagnoses and misdiagnoses of adults with autism spectrum disorder.
Missed diagnoses and misdiagnoses of adults with autism spectrum disorder.
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DOI：
10.1007/s00406-020-01189-w
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发表时间：
2022-03
影响因子：
4.7
通讯作者：
Aguglia E
中科院分区：
文献类型：
--
作者：
Fusar-Poli L;Brondino N;Politi P;Aguglia E
自闭症谱系障碍（ASD）是一组终身神经发育障碍，影响1.5%的普通人群。本研究的目的是评估一组在意大利两所大学中心首次诊断为ASD的成年人的精神病史。在使用标准化工具（即，ADOS-2、ADI-R）。样本包括161名参与者，其中114名（79.5%）为男性。诊断的中位年龄为23岁（范围18-55），中位智商为100（范围30-145）。心理健康专业人员的第一次评估是在中位年龄13岁时进行的，第一次评估和ASD诊断之间的差距为11年。33.5%的参与者从未接受过精神病诊断，而其余样本接受过一种或多种与ASD不同的诊断。最常见的既往诊断是智力残疾、精神病、人格障碍和抑郁症。在诊断年龄和ADOS-2评分方面存在性别差异。我们的研究结果为儿童和成人精神科医生提供了重要的信息。考虑到自闭症的患病率和并发精神疾病的高发病率，临床医生在鉴别诊断过程中考虑ASD是很重要的。
Autism spectrum disorder (ASD) is a group of life-long neurodevelopmental disorders affecting 1.5% of the general population. The present study aimed to evaluate the psychiatric history of a group of adults who received the first diagnosis of ASD in two Italian university centers. Diagnoses of ASD were confirmed by a team of psychiatrists with wide expertise in the field, after the administration of standardized tools (i.e., ADOS-2, ADI-R). The sample comprised 161 participants, of which 114 (79.5%) were males. The median age of diagnosis was 23 years (range 18–55), with a median IQ of 100 (range 30–145). The first evaluation by a mental health professional was performed at a median age of 13 years, with a gap of 11 years between the first evaluation and the diagnosis of ASD. 33.5% of participants had never received a psychiatric diagnosis, while the rest of the sample had received one or more diagnoses different from ASD. The most common past diagnoses were intellectual disability, psychoses, personality disorders, and depression. Sex differences were detected in the age of diagnosis and ADOS-2 scores. Our results provide important information for both child and adult psychiatrists. Given the prevalence of autism and the high rates of co-occurrent psychiatric conditions, it is important for clinicians to consider ASD in the differential diagnostic process.
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DOI：
10.1176/appi.ajp.2010.09101470
发表时间：
2010-11
期刊：
The American journal of psychiatry
影响因子：
--
作者：
Constantino JN;Zhang Y;Frazier T;Abbacchi AM;Law P
通讯作者：
Law P
影响因子：
3.1
作者：
Bertelli, Marco;Scuticchio, Daniela;Monchieri, Sergio
通讯作者：
Monchieri, Sergio
DOI：
10.1007/978-3-030-26276-1_10
发表时间：
2019-01-01
期刊：
PSYCHOPATHOLOGY IN ADOLESCENTS AND ADULTS WITH AUTISM SPECTRUM DISORDERS
影响因子：
--
作者：
De Cagna, Francesca;Squillari, Edoardo;Fusar-Poli, Laura
通讯作者：
Fusar-Poli, Laura
DOI：
10.1111/j.2517-6161.1995.tb02031.x
发表时间：
1995-01-01
影响因子：
5.8
作者：
BENJAMINI, Y;HOCHBERG, Y
通讯作者：
HOCHBERG, Y
影响因子：
4.5
作者：
Giarelli E;Wiggins LD;Rice CE;Levy SE;Kirby RS;Pinto-Martin J;Mandell D
通讯作者：
Mandell D