Respiratory impedance in healthy subjects: baseline values and bronchodilator response
Respiratory impedance in healthy subjects: baseline values and bronchodilator response
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DOI：
10.1183/09031936.00126212
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发表时间：
2013-12-01
影响因子：
24.3
通讯作者：
Hantos, Zoltan
中科院分区：
文献类型：
--
作者：
Oostveen, Ellie;Boda, Krisztina;Hantos, Zoltan
由于受试者对合作的要求最低，强迫振荡技术越来越多地被用于常规肺功能测试。然而，健康成年人在基线和支气管扩张后的呼吸阻抗值还没有建立起全面的和设备无关的值。这项多中心研究的目的是收集18至80岁健康高加索受试者4至26赫兹的阻抗数据。我们使用了五种不同的设备来评估基线值和支气管扩张剂的反应。总共检查了368名受试者。尽管对人体测量进行了调整，但中心之间的阻抗频谱在频率依赖性上不同，因此不能合并。然而，除20和25赫兹外的所有频率下的电阻，以及低频(
Because of the minimal demand for cooperation by the subject, the forced oscillation technique is increasingly employed in routine lung function testing. However, comprehensive and device-independent values of respiratory impedance at baseline and after bronchodilation have not been established for healthy adults.The aim of this multicentre study was to collect impedance data from 4 to 26 Hz in healthy Caucasian subjects between 18 and 80 years of age. Five different devices were employed to assess baseline values and the bronchodilator response.Altogether, 368 subjects were examined. Despite adjustment for anthropometry, the impedance spectra differed in frequency dependence between the centres, and hence could not be pooled. However, resistance at all frequencies except 20 and 25 Hz, and the low-frequency (