Colorectal Cancer Screening

Colorectal Cancer Screening
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DOI:
10.1016/j.suc.2015.05.007
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发表时间:
2015-10-01
影响因子:
3.1
通讯作者:
Garborg, Kjetil
Garborg, Kjetil
中科院分区:
医学3区
文献类型:
--
作者:
Garborg, Kjetil

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结直肠癌(CRC)是西方世界癌症发病率和死亡率的主要原因。手术和医疗管理的进步已经改善了结果;然而,当在症状阶段检测到CRC时,其预后往往很差。大多数结直肠癌病例是由可切除的明确的前驱病变发展而来的,无症状的,可治愈的疾病可以通过方便的非侵入性检测来检测。这些特征使CRC成为筛选的合适候选者,并且有几种选择可用。本文概述了证据确立CRC筛查试验随着沿着讨论新的测试和正在进行的研究。
Colorectal cancer (CRC) is a leading cause of cancer morbidity and mortality in the Western world. Advances in surgical and medical management have led to improved outcomes; however, the prognosis of CRC is often poor when detected at a symptomatic stage. Most cases of CRC develop over years from removable well-defined precursor lesions, and asymptomatic, curable disease may be detected by convenient noninvasive tests. These features make CRC a suitable candidate for screening, and several options are available. This article outlines the evidence for established CRC screening tests along with a discussion on newer tests and ongoing research.