Formation of phosphate-containing calcium fluoride at the expense of enamel, hydroxyapatite and fluorapatite.
Formation of phosphate-containing calcium fluoride at the expense of enamel, hydroxyapatite and fluorapatite.
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DOI：
10.1159/000262073
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发表时间：
1995
期刊：
影响因子：
4.2
通讯作者：
J. Christoffersen;M. R. Christoffersen;J. Arends;E. S. Leonardsen
中科院分区：
文献类型：
--
作者：
J. Christoffersen;M. R. Christoffersen;J. Arends;E. S. Leonardsen
在龋齿过程中，发生涉及钙、磷酸盐、氢和氟离子作为主要物质的复杂反应。在这项研究中，在明确定义的条件下，在釉质，羟基磷灰石（HAP）和氟磷灰石（FAP）的悬浮液中发生的沉淀和溶解反应进行了研究。监测pH和pF;在选定的时间测量钙和磷酸盐浓度;通过红外线、X射线衍射和透射电子显微镜检查固相。含磷酸盐的氟化钙晶体CaF 2（P）的沉淀可导致钙离子浓度的严重降低和氢离子从沉淀的磷酸盐中的释放。这些反应导致釉质、HAP甚至FAP的大量溶解。更多的添加的矿物溶解与50 mmol/l的氟化物比与10 mmol/l的氟化物，主要是由于更大的减少钙离子浓度。这项工作表明，含磷酸盐的氟化钙是最有可能的一个重要的化合物被认为在龋齿的过程。
During the caries process complex reactions involving calcium, phosphate, hydrogen and fluoride ions as main species take place. In this study the precipitation and dissolution reactions occurring in suspensions of enamel, hydroxyapatite (HAP) and fluorapatite (FAP) on addition of fluoride were investigated under well-defined conditions. pH and pF were monitored; calcium and phosphate concentrations were measured at selected times; the solid phases were examined by infra-red, X-ray diffraction and transmission electron microscopy. Precipitation of phosphate-containing calcium fluoride crystals, CaF2(P), can cause severe reduction in the calcium ion concentration and release of hydrogen ions from the precipitated phosphate. These reactions result in considerable dissolution of enamel, HAP and even of FAP. More of the added mineral dissolves with 50 mmol/l fluoride than with 10 mmol/l fluoride, mainly due to the greater reduction in calcium ion concentration. This work shows that phosphate-containing calcium fluoride is most likely an important compound to be considered in the caries process.