Does response on the PHQ-9 Depression Questionnaire predict subsequent suicide attempt or suicide death?
Does response on the PHQ-9 Depression Questionnaire predict subsequent suicide attempt or suicide death?
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DOI：
10.1176/appi.ps.201200587
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发表时间：
2013-12-01
期刊：
影响因子：
--
通讯作者：
Ludman EJ
中科院分区：
文献类型：
--
作者：
Simon GE;Rutter CM;Peterson D;Oliver M;Whiteside U;Operskalski B;Ludman EJ
随着标准抑郁问卷在临床实践中的使用增加，临床医生将经常遇到报告自杀意念的患者。我们研究是否回答简短的自我报告抑郁问卷预测随后的自杀企图或自杀死亡。来自一个大型综合卫生系统的电子记录被用来将PHQ9抑郁问卷从门诊就诊与随后的自杀企图和自杀死亡联系起来。84，418名13岁及以上的门诊患者在2007年1月1日至2011年12月31日期间完成了207，625份问卷。电子医疗记录、保险索赔和死亡证明数据在该样本中确定了709例随后的自杀企图和46例自杀死亡。一年内非致命性或致命性自杀企图的累积风险从报告自杀意念“根本没有”的0.4%增加到报告自杀意念“几乎每天”的4%。自我报告的自杀意念仍然是一个强有力的预测随后的自杀企图调整后的年龄，性别，治疗史，和整体抑郁症的严重程度。一年内自杀死亡的累积风险从报告自杀意念“根本没有”的0.03%增加到报告自杀意念“几乎每天”的0.3%。在调整年龄、性别、治疗史和总体抑郁严重程度后，自我报告的自杀意念仍然是随后自杀死亡的中度预测因子。对PHQ9抑郁问卷第9项的回答确定了自杀企图或死亡风险增加的门诊患者。这种过度风险在几天内出现，并持续增长几个月，表明自杀意念是一种持久的脆弱性，而不是短期危机。
As use of standard depression questionnaires in clinical practice increases, clinicians will frequently encounter patients reporting suicidal ideation. We examine whether responses to a brief self-report depression questionnaire predict subsequent suicide attempt or suicide death. Electronic records from a large integrated health system were used to link PHQ9 depression questionnaires from outpatient visits to subsequent suicide attempts and suicide deaths. 84,418 outpatients aged 13 and older completed 207,625 questionnaires between 1/1/2007 and 12/31/2011. Electronic medical records, insurance claims, and death certificate data identified 709 subsequent suicide attempts and 46 suicide deaths in this sample. Cumulative risk of non-fatal or fatal suicide attempt over one year increased from 0.4% among those reporting suicidal ideation “not at all” to 4% among those reporting suicidal ideation “nearly every day”. Self-reported suicidal ideation remained a strong predictor of subsequent suicide attempt after adjusting for age, sex, treatment history, and overall depression severity. Cumulative risk of suicide death over one year increased from 0.03% among those reporting suicidal ideation “not at all” to 0.3% among those reporting suicidal ideation “nearly every day”. Self-reported suicidal ideation remained a moderate predictor of subsequent suicide death after adjusting for age, sex, treatment history, and overall depression severity. Response to item 9 of the PHQ9 depression questionnaire identifies outpatients at increased risk for suicide attempt or death. This excess risk emerges over several days and continues to grow for several months, indicating that suicidal ideation is an enduring vulnerability rather than a short-term crisis.
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影响因子：
5
作者：
MOYER, LA;BOYLE, CA;POLLOCK, DA
通讯作者：
POLLOCK, DA
影响因子：
7
作者：
Kroenke, Kurt;Spitzer, Robert L.;Loewe, Bernd
通讯作者：
Loewe, Bernd
影响因子：
1.8
作者：
Hvid, Marianne;Vangborg, Kerstin;Wang, August G.
通讯作者：
Wang, August G.
影响因子：
4.7
作者：
Marasinghe, Rohana B.;Edirippulige, Sisira;Jiffry, Mohamad T. M.
通讯作者：
Jiffry, Mohamad T. M.
影响因子：
39.2
作者：
Gaynes, BN;West, SL;Lohr, KN
通讯作者：
Lohr, KN