Bifunctional nanocapsules for magnetic resonance imaging and photodynamic therapy
Bifunctional nanocapsules for magnetic resonance imaging and photodynamic therapy
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DOI：
10.1039/c6ra22831c
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发表时间：
2016-11
期刊：
影响因子：
3.9
通讯作者：
Hecheng Zhang;Shan Peng;Suying Xu;Zhengguang Chen
中科院分区：
文献类型：
--
作者：
Hecheng Zhang;Shan Peng;Suying Xu;Zhengguang Chen
本文报道了利用阳离子（Ca 2 +/Gd 3+）诱导部分水解的α-乳清蛋白自组装制备双功能纳米胶囊。所制备的纳米微球，封装光敏剂（玫瑰红）和Gd 3+离子，显示了巨大的潜力，磁共振成像和光动力学治疗的靶向方式。
Here we present the fabrication of bifunctional nanocapsules via cation (Ca2+/Gd3+) induced self-assembly of partially hydrolysed α-lactalbumin. The prepared nanospheres, encapsulated with photosensitizer (Rose Bengal) and Gd3+ ion, show great potentials for magnetic resonance imaging and photodynamic therapy with a target-specific manner.