Grading scale for prediction of outcome in primary intracerebral hemorrhages
Grading scale for prediction of outcome in primary intracerebral hemorrhages
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DOI：
10.1161/strokeaha.106.478222
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发表时间：
2007-05-01
期刊：
影响因子：
8.3
通讯作者：
Gonzalez-Cornejo, Salvador
中科院分区：
文献类型：
--
作者：
Ruiz-Sandoval, Jose L.;Chiquete, Erwin;Gonzalez-Cornejo, Salvador
背景和目的--这项研究旨在独立得出脑出血分级量表(ICH-GS)，用于预测3项预后指标。方法：我们评估了378例入院时和随后30天内的原发性脑出血患者。通过住院和30天死亡率的多变量模型确定独立的预测因素。根据每个预测指标的预后表现为其分配分数。结果：年龄、格拉斯哥昏迷评分、脑出血部位、脑出血量、脑室内扩张均为ICH评分的独立预测因素。然而，不同的临界点和评分大大提高了预测者的预后能力。与ICH评分相比，ICH-GS在3项预后指标中解释的差异更大，在预测住院和30d死亡率方面具有更高的敏感性，在预测30d功能预后方面也同样表现良好。结论：ICH-GS是一个简单而稳健的预测住院和30d死亡率的量表，30d功能状态良好，具有同等的性能。
Background and Purpose - This study aimed to independently derive an intracerebral hemorrhage grading scale ( ICH-GS) for prediction of 3 outcome measures.Methods - We evaluated 378 patients with primary ICH at hospital arrival and during the next 30 days. Independent predictors were identified by multivariate models of in-hospital and 30-day mortality. Points were allotted to each predictor based on its prognostic performance. ICH-GS was also evaluated to predict good 30-day functional status and ICH-GS was compared with the ICH score as the reference scoring system.Results - Independent predictors were age, Glasgow Coma Scale, ICH location, ICH volume, and intraventricular extension, all components of the ICH score. Nevertheless, different cutoffs and scoring improved substantially the prognostic power of the predictors. Compared with the ICH score, ICH-GS explained more variance in the 3 outcome measures, had higher sensitivity in predicting in-hospital and 30-day mortality, and performed equally well in predicting good functional outcome at 30 days follow up.Conclusions - The derived ICH-GS is a simple yet robust scale in predicting in-hospital and 30-day mortality, as well as good 30-day functional status, with equivalent performance.