Long-term effect of body weight-supported treadmill training in Parkinson's disease: A randomized controlled trial
Long-term effect of body weight-supported treadmill training in Parkinson's disease: A randomized controlled trial
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DOI：
10.1053/apmr.2002.34603
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发表时间：
2002-10-01
影响因子：
4.3
通讯作者：
Kang, J
中科院分区：
文献类型：
--
作者：
Miyai, I;Fujimoto, Y;Kang, J
目的：研究体重支持平板运动训练（BWSTT）是否对帕金森病（PD）患者有长期益处。设计：随机对照试验。地点：日本神经系统疾病住院康复单位。参与者：24名患者（Hoehn和Yahr 2.5或3级）（简易精神状态检查评分，>27）。患者随机接受45分钟的BWSTT治疗主要结果测量：在基线和1、2、3和6个月时评估结果测量。措施包括统一帕金森氏病评定量表（APIRS），步行速度（S/10米），和步数为10米步行作为参数的步幅length.Results：4例患者需要修改的药物在随访期间。分析了20例未使用改良药物的患者（BWSTT，n=11; PT，n=9）的功能结局。年龄、PD持续时间、性别和药物剂量相当。基线时，两组患者的心率（BWSTT=33.3; PT=32.6）、速度（BWSTT=10.8; PT=11.5）和步数（BWSTT=23.4; PT=22.8）无差异。BWSTT组在1个月时的Ambal速度方面的改善明显大于PT组（Mann-Whitney U检验，多重比较的Bonferroni调整）（BWSTT=8.5; PT=10.8; P
Objective: To investigate whether body weight-supported treadmill training (BWSTT) is of long-term benefit for patients with Parkinson's disease (PD).Design: Randomized controlled trial.Setting: Inpatient rehabilitation unit for neurologic diseases in Japan.Participants: Twenty-four patients (Hoehn and Yahr stages 2.5 or 3) who were not demented (Mini-Mental State Examination score, >27).Interventions: Patients were randomized to receive either a 45-minute session of BWSTT (up to 20% of body weight supported) or conventional physical therapy (PT) for 3 days a week for 1 month.Main Outcome Measures: Outcome measures were evaluated at baseline and at 1, 2, 3, and 6 months. Measures included the Unified Parkinson's Disease Rating Scale (UPDRS), ambulation speed (s/10m), and number of steps taken for a 10-m walk as a parameter for stride length.Results: Four patients needed modification of medications in the follow-up period. Twenty patients (BWSTT, n=11; PT, n=9) without modified medications were analyzed for functional outcome. Age, duration of PD, gender, and doses of medications were comparable. There was no difference in the baseline UPDRS (BWSTT=33.3; PT=32.6), speed (BWSTT=10.8; PT=11.5), and steps (BWSTT=23.4; PT=22.8). The BWSTT group had significantly greater improvement than the PT group (Mann-Whitney U test, Bonferroni adjustment for multiple comparison) in ambulation speed at 1 month (BWSTT=8.5; PT=10.8; P