Snake modeling and distance transform approach to vascular centerline extraction and quantification
Snake modeling and distance transform approach to vascular centerline extraction and quantification
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DOI：
10.1016/s0895-6111(03)00040-5
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发表时间：
2003-11-01
影响因子：
5.7
通讯作者：
Afzali-Kusha, A
中科院分区：
文献类型：
--
作者：
Maddah, M;Soltanian-Zadeh, H;Afzali-Kusha, A
A new method for fully automated centerline extraction and quantification of microvascular structures in confocal microscopy (CM) images is presented. Our method uses the idea of active contour models as well as path planning and distance transforms for the three-dimensional centerline extraction of elongated objects such as vessels. The proposed approach is especially efficient for centerline extraction of complex branching structures. The method performance is validated in several CM images of both normal and stroked rat brains as well as simulated objects. The results confirm the efficiency of the proposed method in extracting the medial curve of vessels, which is essential for the computation of quantitative parameters. (C) 2003 Elsevier Ltd. All rights reserved.
