Antibiotic prescription behaviours in Lao People's Democratic Republic: a knowledge, attitude and practice survey.
Antibiotic prescription behaviours in Lao People's Democratic Republic: a knowledge, attitude and practice survey.
复制标题
老挝人民民主共和国的抗生素处方行为：一项知识，态度和实践调查。
DOI：
10.2471/blt.14.142844
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发表时间：
2015-04-01
影响因子：
11.1
通讯作者：
Jacobs J
中科院分区：
文献类型：
--
作者：
Quet F;Vlieghe E;Leyer C;Buisson Y;Newton PN;Naphayvong P;Keoluangkhot V;Chomarat M;Longuet C;Steenkeste N;Jacobs J
评估在老挝人民民主共和国工作的医生的抗生素处方做法及其对当地抗生素耐药模式的了解。在4个省的25家公立医院参加晨会的医生被要求完成一项知识、态度和实践调查。调查问卷包含43个选择题，医生在会面时回答。有效率为83.4%（386/463）。270名医生（59.8%）表示他们对抗生素的了解不足。耐甲氧西林金黄色葡萄球菌中仅有14.0%（54/386）认为可能存在头孢菌素交叉耐药。大多数参与者不了解当地伤寒沙门菌（211/385,54.8%）和医院获得性肺炎（253/384,65.9%）的抗生素耐药性情况。115名参与者认为不必要的抗生素处方是无害的，148名参与者认为当地可获得的仿制抗生素质量差。近四分之三（280/386）的参与者认为很难选择正确的抗生素。大多数参与者（373/386）欢迎有关抗生素处方的教育计划，65.0%（249/383）更喜欢本地抗生素指南，而不是国际抗生素指南。老挝人民民主共和国的医生似乎倾向于抗生素处方干预。卫生当局应考虑一项能力建设规划，将抗生素处方和医院感染控制结合起来。
To assess the antibiotic prescribing practices of doctors working in the Lao People's Democratic Republic and their knowledge of local antibiotic resistance patterns. Doctors attending morning meetings in 25 public hospitals in four provinces were asked to complete a knowledge, attitude and practice survey. The questionnaire contained 43 multiple choice questions that the doctor answered at the time of the meeting. The response rate was 83.4% (386/463). Two hundred and seventy doctors (59.8%) declared that they had insufficient information about antibiotics. Only 14.0% (54/386) recognized the possibility of cephalosporin cross-resistance in methicillin-resistant Staphylococcus aureus. Most participants had no information about local antibiotic resistance for Salmonella Typhi (211/385, 54.8%) and hospital-acquired pneumonia (253/384, 65.9%). Unnecessary antibiotic prescriptions were considered as harmless by 115 participants and 148 considered locally-available generic antibiotics to be of poor quality. Nearly three-quarters (280/386) of participants agreed that it was difficult to select the correct antibiotics. Most participants (373/386) welcomed educational programmes on antibiotic prescribing and 65.0% (249/383) preferred local over international antibiotic guidelines. Doctors in the Lao People's Democratic Republic seem to favour antibiotic prescribing interventions. Health authorities should consider a capacity building programme that incorporates antibiotic prescribing and hospital infection control.