ALL-NIGHT SPECTRAL-ANALYSIS OF THE SLEEP EEG IN UNTREATED DEPRESSIVES AND NORMAL CONTROLS
ALL-NIGHT SPECTRAL-ANALYSIS OF THE SLEEP EEG IN UNTREATED DEPRESSIVES AND NORMAL CONTROLS
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DOI：
10.1016/0165-1781(84)90135-5
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发表时间：
1984-01-01
影响因子：
11.3
通讯作者：
MATTHEWS, G
中科院分区：
文献类型：
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作者：
BORBELY, AA;TOBLER, I;MATTHEWS, G
记录了 9 名未服用药物的抑郁症患者和 9 名年龄和性别匹配的正常对照受试者的睡眠情况。整夜睡眠脑电图 (EEG) 频谱分析显示，抑郁组 0.25-2.50 Hz 频段的功率密度显着降低。两组在整个频率范围 (0.25-25.0 Hz) 上积分的功率密度值在前 3 个非快速眼动 [快速眼动]/快速眼动睡眠周期中均呈现下降趋势。在每个周期中，抑郁症患者的数值均低于对照组。结果与睡眠依赖过程的建立在抑郁症患者的睡眠调节中存在缺陷的假设是一致的。
Sleep was recorded in 9 drug-free depressive patients and 9 age- and sex-matched normal control subjects. All-night spectral analysis of the sleep electroencephalogram (EEG) showed a significantly reduced power density in the 0.25-2.50 Hz bands in the depressive group. Power density values integrated over the entire frequency range (0.25-25.0 Hz) exhibited for both groups a decreasing trend over the first 3 non-REM [rapid eye movement]/REM sleep cycles. In each cycle depressives had lower values than controls. The results are consistent with the hypothesis that the build-up of a sleep-dependent process is deficient in the sleep regulation of depressive patients.