Association between temporal orientation and attitudes about BRCA1/2 testing among women of African descent with family histories of breast cancer
Association between temporal orientation and attitudes about BRCA1/2 testing among women of African descent with family histories of breast cancer
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DOI：
10.1016/j.pec.2008.03.021
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发表时间：
2008-08-01
影响因子：
3.5
通讯作者：
Valdimarsdottir, Heiddis B.
中科院分区：
文献类型：
--
作者：
Edwards, Tiffany A.;Thompson, Hayley S.;Valdimarsdottir, Heiddis B.
目的：先前的研究已经确定了非洲裔妇女对BRCA检测的具体态度（赞成和反对），这些态度与参与检测的决定有关。这些测试态度可能部分地由时间取向决定，或者一个人如何从过去、现在和未来的角度看待事件的重要性和他们行为的后果。目前的研究在140名有乳腺癌易感基因突变家族史的非洲裔女性中探讨了时间取向与BRCA检测的利弊之间的关系。方法：参与者完成时间取向和基因检测态度的测量。结果：多变量分析表明，未来取向与测试的感知优点正相关。进一步的分析显示，时间取向与测试对家庭和个人控制健康的消极和积极影响相关的特定项目子集之间存在显著关联。结论：这些结果支持时间取向与有乳腺癌家族史的非洲裔妇女对BRCA检测的态度之间的关联。实践意义：研究结果支持在非洲裔女性BRCA检测决策的未来研究中探索时间取向，以及这种结构在开发决策辅助和定制遗传咨询中的重要性。2008爱思唯尔爱尔兰有限公司版权所有。
Objective: Previous studies have identified specific attitudes (pros and cons) about BRCA testing held by women of African descent that are associated with decisions to participate in testing. These testing attitudes may be determined, in part, by temporal orientation, or how one perceives the significance of events and the consequences of their actions in terms of past, present, and future. The current study explored the relationship between temporal orientation and pros and cons of BRCA testing among 140 women of African descent with a family history suggestive of a genetic mutation predisposing to breast cancer.Methods: Participants completed measures of temporal orientation and genetic testing attitudes.Results: Multivariate analyses indicated that future orientation was positively associated with perceived pros of testing. Additional analyses revealed significant associations between temporal orientation and specific item subsets related to the negative and positive impact of testing on family and personal control over one's health.Conclusion: These results support an association between temporal orientation and attitudes about BRCA testing among women of African descent with family histories of breast cancer.Practice implications: Findings support exploration of temporal orientation in future research on BRCA testing decisions among women of African descent and this construct's importance in developing decision aids and tailoring genetic counseling. (c) 2008 Elsevier Ireland Ltd. All rights reserved.