Peers and parents: a comparison between neural activation when winning for friends and mothers in adolescence
Peers and parents: a comparison between neural activation when winning for friends and mothers in adolescence
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DOI：
10.1093/scan/nsw136
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发表时间：
2017-03-01
影响因子：
4.2
通讯作者：
Crone, Eveline A.
中科院分区：
文献类型：
--
作者：
Braams, Barbara R.;Crone, Eveline A.
奖励确实能引起腹侧纹状体的活动。最近的研究表明，替代奖励会引起类似的激活。腹侧纹状体对自我奖励的反应在青春期达到高峰。然而，目前还不清楚腹侧纹状体对替代奖励的反应是如何发展的。在这项研究中，我们使用行为和功能磁共振成像数据来测试这个问题。共有233名年龄在9-26岁之间的参与者在扫描仪中玩赌博游戏，他们可以为自己、他们最好的朋友和母亲赢钱或输钱。参与者评估了他们与朋友和母亲的亲密程度，以及他们有多喜欢为他们获胜。这些评分呈正相关。在神经层面上，男性在为朋友获胜时表现出更高的反应，但没有年龄差异。相比之下，在为母亲获胜时，年龄有二次效应，在青春期中期显示出增强的腹侧纹状体活动。此外，年龄和性别之间存在相互作用；对于女性来说，赢得朋友的反应随着年龄的增长比赢得母亲的反应更强烈。总之，本研究为青春期中期母亲的腹侧纹状体反应升高提供了证据，而女孩的腹侧纹状体反应在同龄人中发生了变化。
Rewards reliably elicit ventral striatum activity. More recently studies have shown that vicarious rewards elicit similar activation. Ventral striatum responses to rewards for self peak during adolescence. However, it is currently not well understood how ventral striatum responses to vicarious rewards develop. In this study, we test this question using behavioral and fMRI data. A total of 233 participants aged 9-26 years old played a gambling game in the scanner in which they could win or lose money for themselves, their best friend and mother. Participants rated how close they felt to their friend and mother and how much they liked winning for them. These ratings were positively correlated. On the neural level males showed higher responses to winning for a friend, but there were no age differences. In contrast, there was a quadratic effect of age when winning for mother, showing heightened ventral striatum activity in mid-adolescence. Furthermore, there was an interaction between age and sex; for females responses to winning for friends become stronger with age relative to winning for mothers. In conclusion, this study provided evidence for elevated ventral striatumresponses for mothers in mid-adolescence, and a shift in ventral striatum responses towards peers in girls.