Increased proportion of giant platelets and platelet distribution width are better indicators of altered platelet homeostasis than mean platelet volume in liver cirrhosis.
Increased proportion of giant platelets and platelet distribution width are better indicators of altered platelet homeostasis than mean platelet volume in liver cirrhosis.
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与肝硬化中的平均血小板体积相比，巨血小板比例的增加和血小板分布宽度是血小板稳态改变的更好指标。
DOI：
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发表时间：
1988
期刊：
影响因子：
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通讯作者：
A. Girolami
中科院分区：
文献类型：
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作者：
G. Luzzatto;G. De Franchis;F. Fabris;G. Gerunda;A. Girolami
对32例正常人和27例肝硬化伴血小板减少症患者的血小板计数、平均血小板体积（MPV）、巨血小板百分率（MTI）和血小板分布宽度（PDW）进行了测定。MTI和PDW与血小板计数呈线性负相关。LC组MTI和PDW明显高于对照组，MPV无明显差异。结论：MTI和PDW是血小板生成刺激的良好指标，在控制和CL和更好的指标，改变血小板稳态比MPV在LC。
Platelet count, mean platelet volume (MPV), giant platelet percentage, expressed by us as megathrombocytic index (MTI) and platelet distribution width (PDW) have been evaluated in 32 control subjects and in 27 patients suffering from liver cirrhosis (LC) and thrombocytopenia. MTI and PDW were linearly and inversely correlated to platelet count both in controls and patients. MTI and PDW were markedly increased in LC as compared to controls, while MPV was not significantly different. It is concluded that MTI and PDW are good indices of thrombopoietic stimulus both in controls and in CL and better indicators of altered platelet homeostasis than MPV in LC.