Dementia and capsular genu ischemia in patientswith severe bacterial meningitis
Dementia and capsular genu ischemia in patientswith severe bacterial meningitis
复制标题
重症细菌性脑膜炎患者的痴呆和膝关节囊缺血
DOI：
10.1007/s10072-009-0168-x
复制
发表时间：
2010
期刊：
影响因子：
3.3
通讯作者：
Kuroiwa Y
中科院分区：
文献类型：
--
作者：
Naito M;Johkura K;Momoo T;Nomiya T;Kudo Y;Kuroiwa Y
内囊前壁的梗塞引起痴呆，其特征为精神丧失、嗜睡和记忆丧失，但无明显的运动麻痹（囊状神经麻痹综合征）。13例重症细菌性脑膜炎患者中，有6例内囊壁梗塞或脑血流量减少。这6名患者中有4名出现脑膜炎后痴呆，其特征为精神丧失、嗜睡和记忆丧失。在24例病毒性脑膜炎患者中，无一例发生包膜缺血或脑膜炎后痴呆。在严重的细菌性脑膜炎患者中，囊膜缺血可能在脑膜炎后痴呆的发展中起一定作用。在病毒性脑膜炎患者中，没有这种缺血可以解释，至少在一定程度上，脑膜炎后痴呆的罕见性。
Infarction in the genu of the internal capsule causes dementia that is characterized by abulia, lethargy and memory loss without obvious motor palsy (capsular genu syndrome). We found infarction or decreased cerebral blood flow in the genu of the internal capsule in 6 of 13 patients with severe bacterial meningitis. Four of these six patients developed post-meningitis dementia, characterized by abulia, lethargy, and memory loss. Of 24 patients with viral meningitis, none developed capsular genu ischemia or post-meningitis dementia. In patients with severe bacterial meningitis, capsular genu ischemia may play some role in the development of post-meningitis dementia. In patients with viral meningitis, absence of such ischemia may explain, at least in a part, the rarity of post-meningitis dementia.