Olfactory neurones expressing distinct odorant receptor subtypes are spatially segregated in the nasal neuroepithelium
Olfactory neurones expressing distinct odorant receptor subtypes are spatially segregated in the nasal neuroepithelium
复制标题
表达不同气味受体亚型的嗅觉神经元在鼻神经上皮中空间分离
作者：
J. Strotmann;I. Wanner;T. Helfrich;A. Beck;C. Meinken;S. Kubick;H. Breer
用原位杂交技术研究了大鼠嗅上皮中气味受体基因转录本的分布。我们表明，嗅觉神经元亚群表达不同的受体亚型空间分离内的嗅上皮。神经上皮明显划分为不同的表达区，表达特定受体的细胞随机分布在给定的区域内。结构相关的受体亚型具有共同的分布模式。
In situ hybridization techniques have been employed to explore the olfactory epithelium of the rat for the distribution of odorant receptor gene transcripts. We demonstrate that olfactory neurone subpopulations expressing distinct receptor subtypes are spatially segregated within the olfactory epithelium. A compartmentalization of the neuroepithelium into distinct expression zone is apparent, cells expressing a specific receptor are randomly distributed within a given zone. Structurally related receptor subtypes share a common distribution pattern.