Interruption of schistosomiasis transmission in mountainous and hilly regions with an integrated strategy: a longitudinal case study in Sichuan, China.
Interruption of schistosomiasis transmission in mountainous and hilly regions with an integrated strategy: a longitudinal case study in Sichuan, China.
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DOI：
10.1186/s40249-017-0290-6
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发表时间：
2017-04-07
影响因子：
8.1
通讯作者：
Ma X
中科院分区：
文献类型：
--
作者：
Liu Y;Zhong B;Wu ZS;Liang S;Qiu DC;Ma X
在中国，血吸虫病仍然是一个主要的公共卫生问题。自2004年以来，中国制定了控制日本血吸虫传播的综合策略。然而，在中国的山区和丘陵地区，这一阻断血吸虫病传播的综合策略的长期有效性尚不清楚。本次纵向研究旨在评价2005-2014年四川省血吸虫病传播阻断综合策略的效果。从2005年至2014年四川省血吸虫病防治规划年度报告中收集了机器换牛、改善卫生条件、获得清洁水、修建公厕和家庭厕所、灭螺、化疗和健康教育等数据，并对人、牛和钉螺的日本血吸虫感染情况进行了评估，以评估综合战略的效果。从2005年到2014年的10年间，总共使用了536 568台机器来取代牛群，建造了3 284 333个家庭厕所和15 523个公共厕所。向流行村庄的19116 344名居民提供了自来水。总共有230 098公顷的蜗牛栖息地进行了灭螺处理，357 233公顷的蜗牛栖息地得到了环境改善。有7268 138人和840 845头牛接受了吡喹酮化疗。在为期10年的研究期间，向村干部、教师和学童提供了信息、教育和通信材料。综合战略实施10年来，大大减少了人、牛和蜗牛的日本血吸虫感染。自2007年以来，没有发现急性感染，自2012年以来，没有发现血吸虫病病例或受感染的牛。此外，与2005年相比，2014年钉螺栖息地减少了62.39%，自2007年以来，钉螺中没有发现日本血吸虫感染。到2014年，88.9%的流行县实现了血吸虫病传播阻断，2008年在全省实现了血吸虫病传播控制。政府主导、多部门结合的策略对阻断中国山区和丘陵地区血吸虫病传播是有效的。
Schistosomiasis remains a major public health concern in China. Since 2004, an integrated strategy was developed to control the transmission of Schistosoma japonicum in China. However, the long-term effectiveness of this integrated strategy for the interruption of schistosomiasis transmission remains unknown in the mountainous and hilly regions of China until now. This longitudinal study aims to evaluate the effectiveness of the integrated strategy on transmission interruption of schistosomiasis in Sichuan Province from 2005 through 2014. The data regarding replacement of bovines with machines, improved sanitation, access to clean water, construction of public toilets and household latrines, snail control, chemotherapy, and health education were captured from the annual report of the schistosomiasis control programmes in Sichuan Province from 2005 to 2014, and S. japonicum infection in humans, bovines and snails were estimated to evaluate the effectiveness of the integrated strategy. During the 10-year period from 2005 through 2014, a total of 536 568 machines were used to replace bovines, and 3 284 333 household lavatories and 15 523 public latrines were built. Tap water was supplied to 19 116 344 residents living in the endemic villages. A total of 230 098 hm2 snail habitats were given molluscicide treatment, and 357 233 hm2 snail habitats received environmental improvements. There were 7 268 138 humans and 840 845 bovines given praziquantel chemotherapy. During the 10-year study period, information, education and communication (IEC) materials were provided to village officers, teachers and schoolchildren. The 10-year implementation of the integrated strategy resulted in a great reduction in S. japonicum infection in humans, bovines and snails. Since 2007, no acute infection was detected, and no schistosomiasis cases or infected bovines were identified since 2012. In addition, the snail habitats reduced by 62.39% in 2014 as compared to that in 2005, and no S. japonicum infection was identified in snails since 2007. By 2014, 88.9% of the endemic counties achieved the transmission interruption of schistosomiasis and transmission control of schistosmiasis was achieved in the whole province in 2008. The government-directed and multi-department integrated strategy is effective for interrupting the transmission of schistosomiasis in the mountainous and hilly regions of China.