Loading Cu-doped magnesium oxide onto surface of magnetic nanoparticles to prepare magnetic disinfectant with enhanced antibacterial activity

Loading Cu-doped magnesium oxide onto surface of magnetic nanoparticles to prepare magnetic disinfectant with enhanced antibacterial activity
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磁性纳米粒子表面负载铜掺杂氧化镁制备增强抗菌活性的磁性消毒剂

DOI:
10.1016/j.colsurfb.2017.11.010
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发表时间:
2017
期刊:
Colloids and Surfaces B: Biointerfaces
影响因子:
--
通讯作者:
常丽新
常丽新
中科院分区:
其他
文献类型:
--
作者:
张小乐;王巍杰;张一江;曾涛;贾长虹;常丽新

文献摘要

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In this article, Cu-doped magnesium oxide was loaded onto the surface of Fe3O4magnetic nanoparticlesviaa hydrophilic carbon intermediate layer to synthesize Fe3O4@C@MgO-Cu magnetic composite. The potential application as disinfectant in water purification was investigated by examining the antibacterial activity of the Fe3O4@C@MgO-Cu composite toward Gram negativeEscherichia coliand Gram positiveStaphylococcus aureus.The practical bactericidal efficiency in inactivation experiment was also studied and the copper doping amount was optimized. The results show that the as-obtained magnetic composite, with good dispersion and typical multilayer structure, exhibited high antibacterial activity to both strains and the Cu-doping improved the antibacterial performance significantly. Moreover, an increasing bactericidal ability of the nanocomposite was observed with the increasing Cu-doping amount and 312.5 mg L−1of Fe3O4@C@MgO-Cu disinfectant with a 1.5% Cu-doping amount (wt% of MgO) could inactivate 99% of the tested bacteria in normal saline solution within 60 minutes. The Fe3O4@C@MgO-Cu composite, with a high magnetic saturation value of 29.07 emu g−1, can be readily recovered from matrix solution for reuse with an external magnet, which simplified the disinfection operation greatly and avoided the waste of disinfectant.