Nonredundant gap junction functions.
Nonredundant gap junction functions.
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DOI：
10.1152/nips.01430.2002
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发表时间：
2003-06
期刊：
影响因子：
--
通讯作者：
T. W. White
中科院分区：
文献类型：
--
作者：
T. W. White
体内间隙连接通道蛋白分子异质性的需求一直是个谜。最近，在小鼠和果蝇中将一种通道基因替换为另一种通道基因的功能表明，细胞健康不仅取决于间隙连接通讯，还需要正确类型的细胞间通道亚基。
The need for molecular heterogeneity of gap junction channel proteins in vivo has been enigmatic. Recently, functional replacement of one channel gene with another in mice and flies has revealed that cellular health depends not simply on gap junction communication but also requires the correct type of intercellular channel subunit.