Potent achiral agonists of the ghrelin (growth hormone secretagogue) receptor. Part I: Lead identification
Potent achiral agonists of the ghrelin (growth hormone secretagogue) receptor. Part I: Lead identification
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DOI：
10.1016/j.bmcl.2007.09.067
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发表时间：
2007-12-01
影响因子：
2.7
通讯作者：
Sanger, Gareth
中科院分区：
文献类型：
--
作者：
Heightman, Tom D.;Scott, Jackie S.;Sanger, Gareth
高吞吐量筛选结合有效的数据材料和平行合成，导致发现了一系列新型的吲哚线，显示出有效的体外生长素蛋白受体激动剂活性和大鼠胃排空的加速度。 （c）2007 Elsevier Ltd.保留所有权利。
High throughput screening combined with efficient datamining and parallel synthesis led to the discovery of a novel series of indolines showing potent in vitro ghrelin receptor agonist activity and acceleration of gastric emptying in rats. (c) 2007 Elsevier Ltd. All rights reserved.