Evaluating asymptomatic patients with mildly elevated liver enzymes.
Evaluating asymptomatic patients with mildly elevated liver enzymes.
复制标题
评估肝酶轻度升高的无症状患者。
DOI：
10.3949/ccjm.65.3.150
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发表时间：
1998
影响因子：
6.1
通讯作者：
Z. Younossi
中科院分区：
文献类型：
--
作者：
Z. Younossi
由于在1%至4%的无症状患者中发现肝酶升高，因此对所有异常检查的广泛评估将使许多患者面临不必要的风险和医疗费用。另一方面，不评估肝酶的轻微升高可能导致错过潜在可治疗疾病的早期诊断。本综述讨论了转氨酶、碱性磷酸酶和γ-谷氨酰转移酶水平升高的可能原因，并提供了在初级保健环境中评估明显健康患者肝酶值异常的算法。
Because elevated liver enzymes are found in 1% to 4% of asymptomatic persons, extensive evaluation of all abnormal tests would expose many patients to undue risks and medical costs. On the other hand, not evaluating minor elevations of liver enzymes could result in missing the early diagnosis of potentially treatable disorders. This review discusses likely causes of elevated aminotransferase, alkaline phosphatase, and gamma-glutamyl transferase levels and provides algorithms for evaluating abnormal liver enzyme values in apparently healthy patients in the primary care setting.