Decreased expression of methyl methansulfonate and ultraviolet‐sensitive gene clone 81 (Mus81) is correlated with a poor prognosis in patients with hepatocellular carcinoma
Decreased expression of methyl methansulfonate and ultraviolet‐sensitive gene clone 81 (Mus81) is correlated with a poor prognosis in patients with hepatocellular carcinoma
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DOI：
10.1002/cncr.23396
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发表时间：
2008-05
期刊：
影响因子：
6.2
通讯作者：
Fan Wu;Sile Liu;Yi-ming Tao;Di-peng Ou;F. Fang;Lian-yue Yang
中科院分区：
文献类型：
--
作者：
Fan Wu;Sile Liu;Yi-ming Tao;Di-peng Ou;F. Fang;Lian-yue Yang
最近的研究表明，甲基磺酸甲酯和紫外线敏感基因克隆81（Mus81）在维持小鼠染色体稳定性和肿瘤抑制方面至关重要。为了研究其在人类肝细胞癌（HCC）中的作用，目前尚不清楚，作者研究了HCC患者中Mus81表达与预后之间的相关性。
Recent work has demonstrated that methyl methansulfonate and ultraviolet‐sensitive gene clone 81 (Mus81) is critical in the maintenance of chromosome stability and tumor suppression in mice. To investigate its role in human hepatocellular carcinoma (HCC), which currently is unknown, the authors examined the correlation between Mus81 expression and prognosis in patients with HCC.