Age at menarche, total mortality and mortality from ischaemic heart disease and stroke: the Adventist Health Study, 1976-88

Age at menarche, total mortality and mortality from ischaemic heart disease and stroke: the Adventist Health Study, 1976-88
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DOI:
10.1093/ije/dyn251
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发表时间:
2009-02-01
影响因子:
7.7
通讯作者:
Fraser, G. E.
Fraser, G. E.
中科院分区:
医学1区
文献类型:
--
作者:
Jacobsen, B. K.;Oda, K.;Fraser, G. E.

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背景很少有人知道月经初潮年龄和总死亡率和缺血性心脏病和stroke.Methods死亡率之间的关系19462加州基督复临安息日会妇女随访1976年至1988年的队列研究。随访期间共有3313人死亡,其中809人死于缺血性心脏病,378人死于中风。结果初潮早与总死亡率增加相关(P值为线性趋势
Background Little is known about the relationship between age at menarche and total mortality and mortality from ischaemic heart disease and stroke.Methods A cohort study of 19 462 Californian Seventh-Day Adventist women followed-up from 1976 to 1988. A total of 3313 deaths occurred during follow-up, of which 809 were due to ischaemic heart disease and 378 due to stroke.Results An early menarche was associated with increased total mortality (P-value for linear trend