Antifungal amide from leaves of Piper hispidum
Antifungal amide from leaves of Piper hispidum
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DOI：
10.1021/np9703656
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发表时间：
1998-05-01
影响因子：
5.1
通讯作者：
Furlan, M
中科院分区：
文献类型：
--
作者：
Alécio, AC;Bolzani, VD;Furlan, M
Bioactivity-guided fractionation of a CH2Cl2 extract from leaves of Piper hispidum (Piperaceae) yielded a new pyrrolidine amide, N-[7-(3',4'-methylenedioxyphenyl)-2(Z),4(Z)-heptadienoyl] pyrrolidine 1, in addition to two known amides N-[5-(3',4'-methylenedioxyphenyl)-2(E)-pentadienoyl]pyrrolidine and N-[2-(3',4'-methylenedioxy-6'-methoxyphenyl)-2(Z)-propenoyl]pyrrolidine. The structure of compound 1 was elucidated by interpretation of spectral data, including ES-MS. Compound 1 showed antifungal activity against Cladosporium sphaerospermum.
